GGACT | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell of proximal tubule	3 studies	22% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of GGACT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	196.06	245 / 245	100%	6.60	500 / 502
thymus	100%	177.18	651 / 653	99%	4.12	600 / 605
intestine	99%	197.67	961 / 966	99%	6.41	522 / 527
liver	100%	408.39	226 / 226	99%	6.98	400 / 406
pancreas	100%	355.69	328 / 328	98%	4.46	175 / 178
breast	100%	210.55	459 / 459	98%	4.21	1092 / 1118
esophagus	99%	141.41	1433 / 1445	98%	4.33	180 / 183
bladder	100%	166.71	21 / 21	97%	4.91	489 / 504
stomach	100%	195.78	358 / 359	97%	5.83	278 / 286
skin	100%	303.76	1806 / 1809	96%	4.15	452 / 472
uterus	98%	137.14	167 / 170	97%	3.78	446 / 459
ovary	97%	148.21	175 / 180	98%	3.86	422 / 430
kidney	100%	1168.89	89 / 89	95%	5.47	852 / 901
lung	92%	140.28	532 / 578	99%	4.08	1140 / 1155
adrenal gland	100%	426.11	258 / 258	84%	2.71	193 / 230
brain	99%	140.88	2613 / 2642	73%	2.44	518 / 705
lymph node	0%	0	0 / 0	100%	7.33	29 / 29
spleen	100%	208.59	241 / 241	0%	0	0 / 0
adipose	100%	205.07	1202 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	3.86	44 / 45
blood vessel	98%	120.66	1302 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	98%	5.14	78 / 80
heart	87%	68.89	745 / 861	0%	0	0 / 0
muscle	86%	72.77	691 / 803	0%	0	0 / 0
peripheral blood	83%	140.54	771 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

Gene name	GGACT
Protein name	Gamma-glutamylaminecyclotransferase (GGACT) (EC 4.3.2.8) (AIG2-like domain-containing protein 1) (Gamma-glutamylamine cyclotransferase) Gamma-glutamylamine cyclotransferase
Synonyms	A2LD1
Description	FUNCTION: Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. .
Accessions	ENST00000376250.6 ENST00000464500.5 ENST00000455100.2 ENST00000467518.5 ENST00000471912.1 ENST00000683975.1 M0R0M3 ENST00000492399.5 Q9BVM4 M0R217

GO_0042219	Biological process	cellular modified amino acid catabolic process
GO_0070062	Cellular component	extracellular exosome
GO_0005829	Cellular component	cytosol
GO_0061929	Molecular function	gamma-glutamylaminecyclotransferase activity
GO_0005515	Molecular function	protein binding

GGACT report