GFM2 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	6 studies	27% ± 11%	Explore
epithelial cell	4 studies	23% ± 4%	Explore
endothelial cell	3 studies	22% ± 7%	Explore
basal cell	3 studies	19% ± 3%	Explore
GABAergic neuron	3 studies	44% ± 3%	Explore
glutamatergic neuron	3 studies	55% ± 5%	Explore
oligodendrocyte precursor cell	3 studies	23% ± 6%	Explore
neuron	3 studies	20% ± 4%	Explore
astrocyte	3 studies	23% ± 5%	Explore
oligodendrocyte	3 studies	21% ± 3%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	38% ± 11%	Explore
liver	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	966.38	1445 / 1445	100%	17.77	183 / 183
lung	99%	943.49	575 / 578	100%	17.72	1152 / 1155
brain	99%	1180.76	2628 / 2642	99%	16.61	701 / 705
breast	100%	1013.88	459 / 459	99%	23.41	1103 / 1118
stomach	100%	1102.44	359 / 359	99%	17.85	282 / 286
intestine	100%	1102.42	966 / 966	98%	18.46	519 / 527
pancreas	100%	602.66	327 / 328	98%	12.01	174 / 178
uterus	100%	1036.54	170 / 170	97%	17.51	447 / 459
bladder	100%	1056.57	21 / 21	97%	17.05	490 / 504
thymus	100%	1065.00	653 / 653	97%	14.91	587 / 605
prostate	100%	943.16	245 / 245	97%	19.14	487 / 502
kidney	100%	1116.73	89 / 89	96%	18.17	866 / 901
ovary	100%	1003.26	180 / 180	96%	14.09	413 / 430
liver	100%	1234.84	226 / 226	96%	17.44	389 / 406
skin	100%	1428.93	1809 / 1809	96%	23.37	452 / 472
adrenal gland	100%	2012.87	258 / 258	96%	26.25	220 / 230
adipose	100%	989.84	1204 / 1204	0%	0	0 / 0
muscle	100%	1561.53	803 / 803	0%	0	0 / 0
spleen	100%	1012.15	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	21.35	45 / 45
blood vessel	100%	929.51	1333 / 1335	0%	0	0 / 0
heart	97%	1542.65	832 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	93%	14.33	27 / 29
eye	0%	0	0 / 0	90%	13.42	72 / 80
peripheral blood	71%	752.38	661 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0032790	Biological process	ribosome disassembly
GO_0070126	Biological process	mitochondrial translational termination
GO_0070125	Biological process	mitochondrial translational elongation
GO_0032543	Biological process	mitochondrial translation
GO_0005759	Cellular component	mitochondrial matrix
GO_0005525	Molecular function	GTP binding
GO_0003746	Molecular function	translation elongation factor activity
GO_0005515	Molecular function	protein binding
GO_0003924	Molecular function	GTPase activity

Gene name	GFM2
Protein name	Mitochondrial ribosome-releasing factor 2 Ribosome-releasing factor 2, mitochondrial (RRF2mt) (EC 3.6.5.-) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2) (Elongation factor G2) (hEFG2) GTP dependent ribosome recycling factor mitochondrial 2
Synonyms	EFG2 MSTP027
Description	FUNCTION: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis . Acts in collaboration with MRRF . Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts . GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit . Not involved in the GTP-dependent ribosomal translocation step during translation elongation . .
Accessions	D6RF75 D6RAL1 ENST00000509097.1 ENST00000296805.8 [Q969S9-1] ENST00000509430.5 [Q969S9-1] A0A6M4C975 ENST00000427854.6 [Q969S9-5] ENST00000506778.1 ENST00000345239.6 [Q969S9-2] Q969S9

GFM2 report