GCNA report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0106300Biological processprotein-DNA covalent cross-linking repair
GO_0005694Cellular componentchromosome
GO_0005654Cellular componentnucleoplasm
GO_0016605Cellular componentPML body
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0032184Molecular functionSUMO polymer binding

IV. Literature review

[source]
Gene nameGCNA
Protein nameAlternative protein ACRC
Germ cell nuclear acidic protein (Acidic repeat-containing protein) (Germ cell nuclear acidic peptidase) (Germ cell nuclear antigen)
SynonymsACRC
DescriptionFUNCTION: May play a role in DNA-protein cross-links (DPCs) clearance through a SUMO-dependent recruitment to sites of DPCs, ensuring the genomic stability by protecting germ cells and early embryos from various sources of damage . Can resolve the topoisomerase II (TOP2A) DPCs (By similarity). .

AccessionsENST00000373696.8
L8E9I9
Q96QF7
ENST00000373695.1