GBX2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GBX2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GBX2 at tissue level.

III. Associated gene sets

GO_0021794Biological processthalamus development
GO_0021568Biological processrhombomere 2 development
GO_0021555Biological processmidbrain-hindbrain boundary morphogenesis
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0051960Biological processregulation of nervous system development
GO_0001755Biological processneural crest cell migration
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0001569Biological processbranching involved in blood vessel morphogenesis
GO_0021930Biological processcerebellar granule cell precursor proliferation
GO_0021884Biological processforebrain neuron development
GO_0042472Biological processinner ear morphogenesis
GO_0021549Biological processcerebellum development
GO_0048483Biological processautonomic nervous system development
GO_0007399Biological processnervous system development
GO_0007411Biological processaxon guidance
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0061629Molecular functionRNA polymerase II-specific DNA-binding transcription factor binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0000979Molecular functionRNA polymerase II core promoter sequence-specific DNA binding

IV. Literature review

[source]
Gene nameGBX2
Protein nameHomeobox protein GBX-2 (Gastrulation and brain-specific homeobox protein 2)
Gastrulation brain homeobox 2
Synonyms
DescriptionFUNCTION: May act as a transcription factor for cell pluripotency and differentiation in the embryo.

AccessionsENST00000551105.1
P52951
F8VY47
ENST00000306318.5