GBP6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GBP6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GBP6 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0050830Biological processdefense response to Gram-positive bacterium
GO_0042832Biological processdefense response to protozoan
GO_0042742Biological processdefense response to bacterium
GO_0071346Biological processcellular response to type II interferon
GO_0070062Cellular componentextracellular exosome
GO_0031410Cellular componentcytoplasmic vesicle
GO_0005525Molecular functionGTP binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameGBP6
Protein nameGuanylate-binding protein 6 (EC 3.6.5.-) (GTP-binding protein 6) (GBP-6) (Guanine nucleotide-binding protein 6)
Synonyms
DescriptionFUNCTION: Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens, such as bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity). Confers protection to several pathogens, including the bacterial pathogens Listeria monocytogenes and Mycobacterium bovis BCG as well as the protozoan pathogen Toxoplasma gondii (By similarity). .

AccessionsQ6ZN66
ENST00000370456.5 [Q6ZN66-1]