GALP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GALP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GALP at tissue level.

III. Associated gene sets

GO_0050829Biological processdefense response to Gram-negative bacterium
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0032868Biological processresponse to insulin
GO_0007218Biological processneuropeptide signaling pathway
GO_0032098Biological processregulation of appetite
GO_0008150Biological processbiological_process
GO_0042595Biological processbehavioral response to starvation
GO_0005575Cellular componentcellular_component
GO_0005576Cellular componentextracellular region
GO_0005179Molecular functionhormone activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGALP
Protein nameGalanin-like peptide
Synonyms
DescriptionFUNCTION: [Isoform 1]: Hypothalamic neuropeptide which binds to the G-protein-coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin-releasing hormone secretion.; FUNCTION: [Isoform 2]: Exhibits potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Exhibits antimicrobial activity against Gram-negative bacterias, inducing bacterial membrane blebbing . .

AccessionsQ9UBC7
ENST00000357330.7 [Q9UBC7-1]
ENST00000590002.1 [Q9UBC7-2]
ENST00000440823.1 [Q9UBC7-2]