GALNT13 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
oligodendrocyte	16 studies	49% ± 14%	Explore
oligodendrocyte precursor cell	16 studies	73% ± 21%	Explore
glutamatergic neuron	12 studies	47% ± 21%	Explore
GABAergic neuron	10 studies	53% ± 21%	Explore
astrocyte	7 studies	36% ± 20%	Explore
interneuron	6 studies	54% ± 29%	Explore
retina horizontal cell	6 studies	54% ± 30%	Explore
retinal cone cell	5 studies	76% ± 27%	Explore
type I pneumocyte	5 studies	27% ± 5%	Explore
neuron	4 studies	38% ± 9%	Explore
endothelial cell	4 studies	33% ± 12%	Explore
granule cell	4 studies	66% ± 30%	Explore
amacrine cell	4 studies	41% ± 25%	Explore
retinal ganglion cell	4 studies	44% ± 22%	Explore
differentiation-committed oligodendrocyte precursor	3 studies	77% ± 7%	Explore
GABAergic interneuron	3 studies	43% ± 15%	Explore
microglial cell	3 studies	37% ± 16%	Explore
GABAergic amacrine cell	3 studies	41% ± 13%	Explore
glycinergic amacrine cell	3 studies	62% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	17 studies	42% ± 18%	Explore
eye	4 studies	29% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	2074.72	2642 / 2642	95%	69.34	673 / 705
adrenal gland	60%	229.48	156 / 258	67%	10.23	153 / 230
lung	56%	154.43	326 / 578	38%	2.28	434 / 1155
breast	58%	265.91	265 / 459	27%	1.40	297 / 1118
prostate	51%	301.27	126 / 245	31%	0.78	158 / 502
adipose	71%	328.23	851 / 1204	0%	0	0 / 0
blood vessel	68%	376.23	911 / 1335	0%	0	0 / 0
uterus	49%	200.24	83 / 170	14%	0.81	65 / 459
bladder	43%	110.90	9 / 21	19%	0.78	94 / 504
ovary	23%	69.47	42 / 180	37%	1.23	157 / 430
pancreas	1%	1.78	4 / 328	38%	1.08	67 / 178
skin	29%	76.90	533 / 1809	8%	0.47	36 / 472
esophagus	4%	8.41	64 / 1445	25%	1.20	45 / 183
intestine	16%	31.03	156 / 966	9%	0.29	45 / 527
stomach	5%	10.91	18 / 359	8%	0.50	23 / 286
kidney	1%	2.11	1 / 89	10%	0.22	90 / 901
thymus	0%	0.92	3 / 653	7%	0.17	40 / 605
eye	0%	0	0 / 0	3%	0.06	2 / 80
tonsil	0%	0	0 / 0	2%	0.04	1 / 45
liver	0%	0	0 / 226	2%	0.06	9 / 406
heart	1%	2.87	12 / 861	0%	0	0 / 0
muscle	0%	0.43	2 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	GALNT13
Protein name	Polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx8 Polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx6 Polypeptide N-acetylgalactosaminyltransferase 13 (EC 2.4.1.41) (Polypeptide GalNAc transferase 13) (GalNAc-T13) (pp-GaNTase 13) (Protein-UDP acetylgalactosaminyltransferase 13) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13) Polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx2-7 Alternative protein GALNT13 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 isoform B Polypeptide N-acetylgalactosaminyltransferase (EC 2.4.1.-) (Protein-UDP acetylgalactosaminyltransferase) Polypeptide N-acetylgalactosaminyltransferase 13
Synonyms	KIAA1918
Description	FUNCTION: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine (GalNAc) residue from UDP-GalNAc to a serine or threonine residue on the protein receptor . Generates GalNAc-O-Ser/Thr structure also known as Tn antigen, which itself is immunogenic but also serves as a precursor for the synthesis of different mucin-type O-glycan core structures . Contributes to the synthesis of O-linked glycans on mucins and proteoglycans of the central nervous system. May promote neurogenesis through glycosylation and stabilization of PDPN (By similarity). .; FUNCTION: [Isoform 1]: Can glycosylate both unmodified peptides and glycopeptides that already contain an O-linked GalNAc sugar. Transfers GalNAc to Thr-/Ser-rich tandem repeats GTTPSPVPTTSTTSAP of MUC5AC, specifically on Thr-3 of non-glycosylated MUC5AC peptide, on Thr-12 and Thr-13 of preglycosylated MUC5AC at Thr-3 (MUC5AC-3), on Thr-3 of preglycosylated MUC5AC at Thr-13 (MUC5AC-13) and on Thr-12 of preglycosylated MUC5AC at Thr-3 and Thr-13 (MUC5AC-3,13). Transfers GalNAc to three consecutive serine/threonine residues on SDC3 forming a triplet-Tn epitope expressed in Purkinje cells of the developing brain. .; FUNCTION: [Isoform 3]: Can glycosylate both unmodified peptides and glycopeptides that already contain an O-linked GalNAc sugar. Transfers GalNAc to Thr-/Ser-rich tandem repeats GTTPSPVPTTSTTSAP of MUC5AC, specifically on Thr-3 of non-glycosylated MUC5AC peptide, on Thr-12 and Thr-13 of preglycosylated MUC5AC at Thr-3 (MUC5AC-3), on Thr-3 of preglycosylated MUC5AC at Thr-13 (MUC5AC-13) and on Thr-12 of preglycosylated MUC5AC at Thr-3 and Thr-13 (MUC5AC-3,13). .
Accessions	A0A1L4BJC0 A0A1L4BJ91 A0A1L4BJA9 Q8IUC8 ENST00000453715.1 A0A1L4BJA8 L8ECM1 ENST00000392825.8 [Q8IUC8-1] H7C2I5 A0A1L4BJB1 H7BZU4 H7C0T6 ENST00000431076.5 C9JLI4 A0A1L4BJA6 ENST00000409237.5 [Q8IUC8-3] ENST00000422126.1 ENST00000434213.1 H7BZG2 A0A1L4BJB0 Q68VJ0 X5DRI3 ENST00000450838.5

GO_0016266	Biological process	O-glycan processing
GO_0018243	Biological process	protein O-linked glycosylation via threonine
GO_0006493	Biological process	protein O-linked glycosylation
GO_0018242	Biological process	protein O-linked glycosylation via serine
GO_0000139	Cellular component	Golgi membrane
GO_0005794	Cellular component	Golgi apparatus
GO_0004653	Molecular function	polypeptide N-acetylgalactosaminyltransferase activity
GO_0030246	Molecular function	carbohydrate binding
GO_0046872	Molecular function	metal ion binding

GALNT13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review