GAL3ST3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GAL3ST3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GAL3ST3 at tissue level.

III. Associated gene sets

GO_0005996Biological processmonosaccharide metabolic process
GO_0030166Biological processproteoglycan biosynthetic process
GO_0009247Biological processglycolipid biosynthetic process
GO_0006790Biological processsulfur compound metabolic process
GO_0009311Biological processoligosaccharide metabolic process
GO_0030309Biological processpoly-N-acetyllactosamine metabolic process
GO_0032580Cellular componentGolgi cisterna membrane
GO_0016020Cellular componentmembrane
GO_0050656Molecular function3'-phosphoadenosine 5'-phosphosulfate binding
GO_0050698Molecular functionproteoglycan sulfotransferase activity
GO_0030246Molecular functioncarbohydrate binding
GO_0001733Molecular functiongalactosylceramide sulfotransferase activity
GO_0005515Molecular functionprotein binding
GO_0050694Molecular functiongalactose 3-O-sulfotransferase activity

IV. Literature review

[source]
Gene nameGAL3ST3
Protein nameGalactose-3-O-sulfotransferase 3 (Gal3ST-3) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 3) (Gal3ST3) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 3)
Synonyms
DescriptionFUNCTION: Transfers a sulfate to position 3 of non-reducing beta-galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha-1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha-1,4)GlcNAc. .

AccessionsENST00000527878.1
Q96A11
ENST00000312006.5