Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 6 studies | 27% ± 8% | |
| epithelial cell | 6 studies | 45% ± 26% | |
| respiratory goblet cell | 6 studies | 35% ± 12% | |
| club cell | 5 studies | 26% ± 9% | |
| secretory cell | 5 studies | 34% ± 14% | |
| squamous epithelial cell | 4 studies | 37% ± 21% |
Insufficient scRNA-seq data for expression of GABRP at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 76% | 1839.91 | 186 / 245 | 52% | 10.22 | 259 / 502 |
| breast | 62% | 6883.86 | 284 / 459 | 56% | 113.92 | 625 / 1118 |
| esophagus | 38% | 2117.68 | 550 / 1445 | 56% | 55.60 | 103 / 183 |
| skin | 69% | 1701.32 | 1246 / 1809 | 11% | 1.57 | 53 / 472 |
| pancreas | 3% | 9.27 | 9 / 328 | 76% | 124.06 | 135 / 178 |
| uterus | 22% | 522.86 | 38 / 170 | 56% | 107.45 | 256 / 459 |
| kidney | 64% | 868.20 | 57 / 89 | 6% | 0.95 | 50 / 901 |
| stomach | 25% | 185.08 | 90 / 359 | 34% | 31.09 | 98 / 286 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 80.99 | 26 / 45 |
| intestine | 7% | 28.79 | 64 / 966 | 31% | 25.33 | 166 / 527 |
| lung | 6% | 30.64 | 32 / 578 | 30% | 22.49 | 343 / 1155 |
| ovary | 1% | 13.24 | 2 / 180 | 33% | 7.69 | 143 / 430 |
| bladder | 5% | 36.81 | 1 / 21 | 17% | 18.66 | 86 / 504 |
| liver | 17% | 62.62 | 38 / 226 | 4% | 7.15 | 18 / 406 |
| adipose | 20% | 133.23 | 240 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.30 | 3 / 80 |
| thymus | 1% | 5.11 | 7 / 653 | 1% | 0.23 | 4 / 605 |
| adrenal gland | 0% | 1.82 | 1 / 258 | 0% | 0 | 0 / 230 |
| muscle | 0% | 1.59 | 3 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 1.01 | 3 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 3.66 | 1 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.95 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0042391 | Biological process | regulation of membrane potential |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_1902711 | Cellular component | GABA-A receptor complex |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_1902495 | Cellular component | transmembrane transporter complex |
| GO_0034707 | Cellular component | chloride channel complex |
| GO_0045202 | Cellular component | synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043005 | Cellular component | neuron projection |
| GO_0004890 | Molecular function | GABA-A receptor activity |
| GO_0030594 | Molecular function | neurotransmitter receptor activity |
| GO_0005254 | Molecular function | chloride channel activity |
| GO_0022851 | Molecular function | GABA-gated chloride ion channel activity |
| Gene name | GABRP |
| Protein name | Gamma-aminobutyric acid type A receptor subunit pi Gamma-aminobutyric acid receptor subunit pi (GABA(A) receptor subunit pi) |
| Synonyms | |
| Description | FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. In the uterus, the function of the receptor appears to be related to tissue contractility. The binding of this pI subunit with other GABA(A) receptor subunits alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone. |
| Accessions | E5RG98 E5RGF7 E5RI57 O00591 ENST00000521481.5 E7EWG0 ENST00000265294.9 ENST00000522868.5 ENST00000519196.5 E5RK74 E5RHU0 ENST00000518525.5 ENST00000519385.5 ENST00000518122.5 ENST00000519598.1 ENST00000521009.5 E5RHF6 |
