Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 9 studies | 43% ± 25% | |
| GABAergic neuron | 6 studies | 48% ± 23% | |
| interneuron | 3 studies | 61% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 45% ± 26% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 89% | 1870.33 | 2339 / 2642 | 47% | 2.69 | 328 / 705 |
| blood vessel | 59% | 426.64 | 786 / 1335 | 0% | 0 | 0 / 0 |
| heart | 45% | 461.71 | 387 / 861 | 0% | 0 | 0 / 0 |
| skin | 9% | 24.56 | 167 / 1809 | 1% | 0.04 | 3 / 472 |
| adipose | 8% | 28.14 | 100 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 2% | 2.64 | 15 / 966 | 5% | 0.20 | 28 / 527 |
| thymus | 0% | 0 | 0 / 653 | 6% | 0.21 | 35 / 605 |
| stomach | 0% | 0 | 0 / 359 | 5% | 0.18 | 14 / 286 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| esophagus | 2% | 5.10 | 32 / 1445 | 1% | 0.01 | 1 / 183 |
| adrenal gland | 0% | 0 | 0 / 258 | 2% | 0.04 | 5 / 230 |
| bladder | 0% | 0 | 0 / 21 | 2% | 0.09 | 8 / 504 |
| lung | 0% | 0.25 | 1 / 578 | 1% | 0.04 | 14 / 1155 |
| uterus | 0% | 0 | 0 / 170 | 1% | 0.18 | 5 / 459 |
| peripheral blood | 1% | 3.47 | 8 / 929 | 0% | 0 | 0 / 0 |
| breast | 0% | 1.47 | 2 / 459 | 0% | 0.03 | 2 / 1118 |
| pancreas | 0% | 0 | 0 / 328 | 1% | 0.01 | 1 / 178 |
| liver | 0% | 0 | 0 / 226 | 0% | 0.01 | 2 / 406 |
| spleen | 0% | 1.52 | 1 / 241 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 3 / 901 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ovary | 0% | 0 | 0 / 180 | 0% | 0 | 0 / 430 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0 | 0 / 502 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1904862 | Biological process | inhibitory synapse assembly |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0060078 | Biological process | regulation of postsynaptic membrane potential |
| GO_0051932 | Biological process | synaptic transmission, GABAergic |
| GO_0007214 | Biological process | gamma-aminobutyric acid signaling pathway |
| GO_0005886 | Cellular component | plasma membrane |
| GO_1902495 | Cellular component | transmembrane transporter complex |
| GO_0098794 | Cellular component | postsynapse |
| GO_0043005 | Cellular component | neuron projection |
| GO_0098982 | Cellular component | GABA-ergic synapse |
| GO_0034707 | Cellular component | chloride channel complex |
| GO_0045202 | Cellular component | synapse |
| GO_1902711 | Cellular component | GABA-A receptor complex |
| GO_0099634 | Cellular component | postsynaptic specialization membrane |
| GO_0032590 | Cellular component | dendrite membrane |
| GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
| GO_0004890 | Molecular function | GABA-A receptor activity |
| GO_0005254 | Molecular function | chloride channel activity |
| GO_0022851 | Molecular function | GABA-gated chloride ion channel activity |
| GO_0008503 | Molecular function | benzodiazepine receptor activity |
| Gene name | GABRA4 |
| Protein name | Gamma-aminobutyric acid type A receptor subunit alpha4 Gamma-aminobutyric acid A receptor alpha 4 isoform B Gamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4) Gamma-aminobutyric acid A receptor alpha 4 isoform A |
| Synonyms | |
| Description | FUNCTION: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. |
| Accessions | ENST00000264318.4 X5DP75 P48169 ENST00000511523.5 ENST00000502874.1 D6RB66 D6R924 ENST00000508560.5 X5D7F5 |