G6PC1 | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	4 studies	50% ± 17%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of G6PC1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	21624.04	226 / 226	97%	317.69	394 / 406
kidney	98%	1622.69	87 / 89	42%	5.39	374 / 901
pancreas	94%	18.12	307 / 328	13%	0.93	24 / 178
stomach	70%	5.53	251 / 359	1%	0.05	4 / 286
blood vessel	63%	4.07	842 / 1335	0%	0	0 / 0
intestine	58%	225.81	564 / 966	1%	0.25	4 / 527
lung	51%	2.78	296 / 578	2%	0.44	20 / 1155
bladder	43%	2.00	9 / 21	6%	0.10	28 / 504
adipose	48%	6.99	574 / 1204	0%	0	0 / 0
spleen	47%	32.85	114 / 241	0%	0	0 / 0
uterus	45%	2.17	77 / 170	1%	0.01	3 / 459
adrenal gland	45%	2.10	115 / 258	0%	0.03	1 / 230
prostate	44%	1.69	107 / 245	0%	0.01	1 / 502
ovary	42%	1.55	76 / 180	0%	0	0 / 430
thymus	42%	1.78	273 / 653	0%	0	0 / 605
peripheral blood	42%	8.26	387 / 929	0%	0	0 / 0
esophagus	40%	2.04	578 / 1445	2%	0.04	3 / 183
breast	41%	3.13	187 / 459	0%	0.03	4 / 1118
brain	37%	1.82	971 / 2642	0%	0.00	2 / 705
skin	31%	1.44	564 / 1809	0%	0.01	2 / 472
heart	26%	1.19	221 / 861	0%	0	0 / 0
muscle	24%	0.83	190 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0046415	Biological process	urate metabolic process
GO_0042632	Biological process	cholesterol homeostasis
GO_0005980	Biological process	glycogen catabolic process
GO_0010468	Biological process	regulation of gene expression
GO_0015760	Biological process	glucose-6-phosphate transport
GO_0035264	Biological process	multicellular organism growth
GO_0051156	Biological process	glucose 6-phosphate metabolic process
GO_0008202	Biological process	steroid metabolic process
GO_0006094	Biological process	gluconeogenesis
GO_0006641	Biological process	triglyceride metabolic process
GO_0042593	Biological process	glucose homeostasis
GO_0005977	Biological process	glycogen metabolic process
GO_0016020	Cellular component	membrane
GO_0005789	Cellular component	endoplasmic reticulum membrane
GO_0042301	Molecular function	phosphate ion binding
GO_0005515	Molecular function	protein binding
GO_0016773	Molecular function	phosphotransferase activity, alcohol group as acceptor
GO_0004346	Molecular function	glucose-6-phosphatase activity

Gene name	G6PC1
Protein name	Glucose-6-phosphatase catalytic subunit 1 (EC 3.1.3.9) (Glucose-6-phosphatase) (G-6-Pase) (G6Pase) (Glucose-6-phosphatase alpha) (G6Pase-alpha) glucose-6-phosphatase (EC 3.1.3.9)
Synonyms	G6PC G6PT
Description	FUNCTION: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels. .
Accessions	ENST00000592383.5 [P35575-2] P35575 ENST00000585489.1 ENST00000253801.7 [P35575-1] K7ELS6

G6PC1 report