Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| respiratory goblet cell | 6 studies | 30% ± 8% | |
| club cell | 5 studies | 19% ± 1% | |
| epithelial cell | 5 studies | 26% ± 10% | |
| secretory cell | 4 studies | 29% ± 8% | |
| enterocyte | 4 studies | 22% ± 2% | |
| duct epithelial cell | 3 studies | 38% ± 16% | |
| squamous epithelial cell | 3 studies | 35% ± 19% |
Insufficient scRNA-seq data for expression of FUT2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 99% | 350.95 | 326 / 328 | 90% | 44.73 | 160 / 178 |
| stomach | 84% | 1249.76 | 303 / 359 | 98% | 57.61 | 280 / 286 |
| intestine | 77% | 1023.37 | 741 / 966 | 98% | 56.74 | 518 / 527 |
| esophagus | 61% | 974.17 | 880 / 1445 | 95% | 40.50 | 174 / 183 |
| ovary | 87% | 116.30 | 157 / 180 | 58% | 8.91 | 250 / 430 |
| uterus | 66% | 92.11 | 113 / 170 | 74% | 25.47 | 339 / 459 |
| lung | 47% | 64.86 | 270 / 578 | 87% | 23.78 | 1008 / 1155 |
| bladder | 71% | 161.14 | 15 / 21 | 63% | 20.30 | 315 / 504 |
| breast | 56% | 122.64 | 255 / 459 | 65% | 9.95 | 729 / 1118 |
| prostate | 86% | 177.01 | 210 / 245 | 15% | 1.35 | 75 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 27.21 | 39 / 45 |
| skin | 78% | 328.44 | 1416 / 1809 | 4% | 0.61 | 19 / 472 |
| brain | 81% | 129.16 | 2151 / 2642 | 0% | 0.01 | 1 / 705 |
| thymus | 68% | 65.74 | 442 / 653 | 10% | 0.88 | 61 / 605 |
| spleen | 55% | 50.23 | 133 / 241 | 0% | 0 | 0 / 0 |
| adrenal gland | 43% | 38.40 | 110 / 258 | 7% | 0.65 | 16 / 230 |
| kidney | 40% | 45.16 | 36 / 89 | 3% | 0.35 | 31 / 901 |
| liver | 3% | 1.73 | 6 / 226 | 14% | 2.07 | 58 / 406 |
| heart | 16% | 12.47 | 136 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 7% | 5.44 | 93 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 7% | 7.74 | 79 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 1.91 | 6 / 929 | 0% | 0 | 0 / 0 |
| muscle | 1% | 1.14 | 5 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005975 | Biological process | carbohydrate metabolic process |
| GO_0009312 | Biological process | oligosaccharide biosynthetic process |
| GO_0006688 | Biological process | glycosphingolipid biosynthetic process |
| GO_0030155 | Biological process | regulation of cell adhesion |
| GO_0042355 | Biological process | L-fucose catabolic process |
| GO_0001936 | Biological process | regulation of endothelial cell proliferation |
| GO_0006486 | Biological process | protein glycosylation |
| GO_0036065 | Biological process | fucosylation |
| GO_0006664 | Biological process | glycolipid metabolic process |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0032580 | Cellular component | Golgi cisterna membrane |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0008107 | Molecular function | galactoside 2-alpha-L-fucosyltransferase activity |
| GO_0031127 | Molecular function | alpha-(1,2)-fucosyltransferase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008417 | Molecular function | fucosyltransferase activity |
| Gene name | FUT2 |
| Protein name | Alternative protein FUT2 Galactoside alpha-(1,2)-fucosyltransferase 2 (Alpha(1,2)FT 2) (Fucosyltransferase 2) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2) (SE2) (Secretor blood group alpha-2-fucosyltransferase) (Secretor factor) (Se) (Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2) (EC 2.4.1.69) (Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2) (EC 2.4.1.344) L-Fucosyltransferase (EC 2.4.1.-) |
| Synonyms | hCG_1998026 SEC2 |
| Description | FUNCTION: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation . Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs (By similarity). Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition . Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway . . |
| Accessions | A0A7M4CF06 A0A7M4CF24 W6E7L2 B3W6G7 Q5XLR8 A0A7M4CF01 A0A7M4CEZ3 A0A7M4CF05 A0A866W333 A0A7L9AZU0 A8K2L2 Q7KZZ1 ENST00000522966.2 A0A7M4CF15 A0A7M4CF09 A0A866VVB6 A0A7M4CF04 A0A866W2E3 A0A7L9AZP2 A0A7M4CF07 A0A7M4CF17 A0A7L9AYG2 A0A7M4CF18 A0A7L9AZK5 A0A7M4CEZ1 A0A866W2E6 A0A7L9AZS2 A0A7M4CF08 A0A7M4CF19 A0A7M4CEY9 A0A7M4CF20 B5B9L6 A0A7M4CF14 A0A7L9AYP3 Q10981 ENST00000425340.3 L8EC57 W6E8M9 A0A7M4CF10 A0A7M4CF21 A0A866W0U4 A0A7M4CEZ4 |
