Insufficient scRNA-seq data for expression of FMO4 at single-cell level.
Insufficient scRNA-seq data for expression of FMO4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 374.32 | 653 / 653 | 98% | 7.31 | 595 / 605 |
| kidney | 100% | 1002.33 | 89 / 89 | 98% | 17.50 | 886 / 901 |
| breast | 100% | 460.56 | 459 / 459 | 98% | 9.50 | 1096 / 1118 |
| liver | 99% | 1309.33 | 224 / 226 | 97% | 25.61 | 395 / 406 |
| ovary | 99% | 359.18 | 179 / 180 | 95% | 6.14 | 409 / 430 |
| skin | 97% | 259.97 | 1758 / 1809 | 97% | 10.76 | 457 / 472 |
| esophagus | 98% | 215.52 | 1418 / 1445 | 94% | 6.87 | 172 / 183 |
| pancreas | 96% | 169.57 | 316 / 328 | 93% | 6.28 | 165 / 178 |
| uterus | 100% | 279.25 | 170 / 170 | 89% | 8.38 | 408 / 459 |
| prostate | 98% | 338.54 | 241 / 245 | 89% | 4.52 | 449 / 502 |
| stomach | 99% | 320.09 | 355 / 359 | 89% | 4.81 | 254 / 286 |
| lung | 94% | 248.73 | 541 / 578 | 93% | 8.74 | 1069 / 1155 |
| intestine | 99% | 350.85 | 953 / 966 | 82% | 4.14 | 433 / 527 |
| bladder | 100% | 220.90 | 21 / 21 | 80% | 4.64 | 405 / 504 |
| brain | 62% | 87.42 | 1642 / 2642 | 88% | 4.42 | 623 / 705 |
| adrenal gland | 97% | 313.98 | 250 / 258 | 36% | 2.02 | 83 / 230 |
| eye | 0% | 0 | 0 / 0 | 100% | 13.83 | 80 / 80 |
| spleen | 100% | 341.84 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 655.38 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 367.86 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 7.72 | 28 / 29 |
| heart | 96% | 301.11 | 829 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 7.48 | 40 / 45 |
| peripheral blood | 53% | 93.10 | 492 / 929 | 0% | 0 | 0 / 0 |
| muscle | 52% | 54.53 | 419 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0097009 | Biological process | energy homeostasis |
| GO_0042178 | Biological process | xenobiotic catabolic process |
| GO_0046322 | Biological process | negative regulation of fatty acid oxidation |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0047822 | Molecular function | hypotaurine dehydrogenase activity |
| GO_0050661 | Molecular function | NADP binding |
| GO_0004499 | Molecular function | N,N-dimethylaniline monooxygenase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0050660 | Molecular function | flavin adenine dinucleotide binding |
| Gene name | FMO4 |
| Protein name | Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Dimethylaniline oxidase 4) (Hepatic flavin-containing monooxygenase 4) (FMO 4) |
| Synonyms | FMO2 |
| Description | FUNCTION: This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. |
| Accessions | P31512 ENST00000367749.4 |