FETUB report

I. Expression across cell types

Insufficient scRNA-seq data for expression of FETUB at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of FETUB at tissue level.

III. Associated gene sets

GO_0007339Biological processbinding of sperm to zona pellucida
GO_0010951Biological processnegative regulation of endopeptidase activity
GO_0007338Biological processsingle fertilization
GO_0008150Biological processbiological_process
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0004869Molecular functioncysteine-type endopeptidase inhibitor activity
GO_0005515Molecular functionprotein binding
GO_0008191Molecular functionmetalloendopeptidase inhibitor activity
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameFETUB
Protein nameFetuin-B (16G2) (Fetuin-like protein IRL685) (Gugu)
Fetuin B
Synonyms
DescriptionFUNCTION: Protease inhibitor required for egg fertilization. Required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). .

AccessionsENST00000435961.5
C9JC68
ENST00000431018.5
ENST00000265029.8 [Q9UGM5-1]
ENST00000382134.7
ENST00000382136.3 [Q9UGM5-2]
ENST00000420570.1
F8WAW1
E9PG08
F8WEP7
Q9UGM5
ENST00000450521.5 [Q9UGM5-1]