FABP6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015908Biological processfatty acid transport
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0006629Biological processlipid metabolic process
GO_0005829Cellular componentcytosol
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005504Molecular functionfatty acid binding
GO_0008289Molecular functionlipid binding

IV. Literature review

[source]
Gene nameFABP6
Protein nameGastrotropin (GT) (Fatty acid-binding protein 6) (Ileal lipid-binding protein) (ILBP) (Intestinal 15 kDa protein) (I-15P) (Intestinal bile acid-binding protein) (I-BABP)
Fatty acid binding protein 6
SynonymsILLBP
ILBP
DescriptionFUNCTION: Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). .; FUNCTION: [Isoform 2]: Essential for the survival of colon cancer cells to bile acid-induced apoptosis. .

AccessionsENST00000523955.5
ENST00000393980.8 [P51161-2]
ENST00000402432.4 [P51161-1]
P51161
H0YB64