F11 | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	3 studies	54% ± 16%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of F11 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	5895.07	226 / 226	96%	35.44	391 / 406
pancreas	100%	1279.06	328 / 328	58%	3.18	104 / 178
kidney	100%	408.10	89 / 89	20%	0.95	181 / 901
lung	85%	140.83	489 / 578	15%	0.51	170 / 1155
stomach	71%	10.48	255 / 359	4%	0.11	12 / 286
intestine	69%	16.24	663 / 966	6%	0.22	32 / 527
brain	63%	6.38	1677 / 2642	1%	0.01	5 / 705
ovary	64%	6.14	115 / 180	0%	0.01	1 / 430
blood vessel	63%	6.48	846 / 1335	0%	0	0 / 0
spleen	48%	9.44	115 / 241	0%	0	0 / 0
muscle	44%	4.35	351 / 803	0%	0	0 / 0
adrenal gland	41%	2.88	105 / 258	2%	0.30	4 / 230
prostate	42%	4.09	102 / 245	0%	0	0 / 502
bladder	38%	2.86	8 / 21	2%	0.07	9 / 504
uterus	38%	4.00	65 / 170	0%	0.03	2 / 459
esophagus	32%	2.73	459 / 1445	5%	0.15	10 / 183
thymus	32%	2.32	212 / 653	0%	0.00	1 / 605
heart	23%	1.60	198 / 861	0%	0	0 / 0
adipose	23%	2.49	273 / 1204	0%	0	0 / 0
breast	16%	1.41	72 / 459	0%	0.00	2 / 1118
peripheral blood	15%	3.01	135 / 929	0%	0	0 / 0
skin	6%	0.54	116 / 1809	0%	0	0 / 472
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0031639	Biological process	plasminogen activation
GO_0007596	Biological process	blood coagulation
GO_0051919	Biological process	positive regulation of fibrinolysis
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0008201	Molecular function	heparin binding
GO_0070009	Molecular function	serine-type aminopeptidase activity
GO_0005515	Molecular function	protein binding
GO_0004252	Molecular function	serine-type endopeptidase activity

Gene name	F11
Protein name	Coagualtion factor XI Coagulation factor XI (FXI) (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) [Cleaved into: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain] Coagulation factor XI
Synonyms
Description	FUNCTION: Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Accessions	ENST00000264691.4 A0A411HAZ9 ENST00000452239.1 ENST00000492972.6 Q9UEG0 P03951 ENST00000403665.7 [P03951-1] D6RB32 X6R3B1 H0Y596

F11 report