Insufficient scRNA-seq data for expression of ERAS at single-cell level.
Insufficient scRNA-seq data for expression of ERAS at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 66.74 | 2628 / 2642 | 62% | 1.25 | 437 / 705 |
uterus | 92% | 24.41 | 157 / 170 | 8% | 0.18 | 37 / 459 |
kidney | 96% | 23.65 | 85 / 89 | 4% | 0.07 | 39 / 901 |
ovary | 87% | 20.07 | 157 / 180 | 11% | 2.96 | 46 / 430 |
prostate | 82% | 14.38 | 202 / 245 | 1% | 0.05 | 5 / 502 |
intestine | 75% | 14.02 | 729 / 966 | 1% | 0.02 | 4 / 527 |
liver | 70% | 15.15 | 158 / 226 | 1% | 0.02 | 6 / 406 |
breast | 59% | 7.10 | 273 / 459 | 1% | 0.02 | 13 / 1118 |
esophagus | 56% | 9.16 | 805 / 1445 | 2% | 0.02 | 3 / 183 |
lung | 54% | 6.19 | 315 / 578 | 2% | 0.05 | 19 / 1155 |
blood vessel | 56% | 6.64 | 745 / 1335 | 0% | 0 | 0 / 0 |
bladder | 48% | 7.90 | 10 / 21 | 1% | 0.25 | 7 / 504 |
adipose | 40% | 4.18 | 481 / 1204 | 0% | 0 | 0 / 0 |
skin | 31% | 3.05 | 563 / 1809 | 1% | 0.01 | 5 / 472 |
stomach | 28% | 3.90 | 101 / 359 | 1% | 0.50 | 2 / 286 |
thymus | 23% | 2.06 | 147 / 653 | 2% | 0.04 | 14 / 605 |
spleen | 22% | 2.04 | 54 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 19% | 1.83 | 50 / 258 | 1% | 0.04 | 2 / 230 |
muscle | 16% | 1.40 | 125 / 803 | 0% | 0 | 0 / 0 |
pancreas | 14% | 1.09 | 46 / 328 | 1% | 0.02 | 2 / 178 |
heart | 8% | 0.64 | 72 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.20 | 2 / 29 |
peripheral blood | 3% | 0.21 | 28 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.06 | 1 / 45 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0005886 | Cellular component | plasma membrane |
GO_0019003 | Molecular function | GDP binding |
GO_0005525 | Molecular function | GTP binding |
GO_0005515 | Molecular function | protein binding |
GO_0003925 | Molecular function | G protein activity |
GO_0003924 | Molecular function | GTPase activity |
Gene name | ERAS |
Protein name | GTPase ERas (E-Ras) (EC 3.6.5.2) (Embryonic stem cell-expressed Ras) |
Synonyms | HRAS2 HRASP |
Description | FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity). . |
Accessions | Q7Z444 ENST00000636362.1 ENST00000338270.1 |