I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 27% ± 8% | |
| mesothelial cell | 4 studies | 19% ± 4% | |
| Mueller cell | 3 studies | 43% ± 6% | |
| interneuron | 3 studies | 19% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 27% ± 8% | |
| mesothelial cell | 4 studies | 19% ± 4% | |
| Mueller cell | 3 studies | 43% ± 6% | |
| interneuron | 3 studies | 19% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 27% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 97% | 5803.63 | 238 / 245 | 95% | 33.11 | 478 / 502 |
| thymus | 95% | 3766.22 | 618 / 653 | 96% | 64.43 | 583 / 605 |
| pancreas | 95% | 2913.38 | 313 / 328 | 92% | 33.52 | 163 / 178 |
| ovary | 90% | 2502.01 | 162 / 180 | 95% | 25.72 | 409 / 430 |
| uterus | 96% | 3937.42 | 164 / 170 | 74% | 18.96 | 338 / 459 |
| bladder | 86% | 2734.90 | 18 / 21 | 63% | 42.02 | 315 / 504 |
| brain | 77% | 7460.83 | 2040 / 2642 | 67% | 19.37 | 474 / 705 |
| skin | 87% | 15561.20 | 1579 / 1809 | 19% | 3.76 | 91 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 35.91 | 1 / 1 |
| esophagus | 46% | 1355.72 | 666 / 1445 | 51% | 11.87 | 94 / 183 |
| kidney | 21% | 416.29 | 19 / 89 | 70% | 8.97 | 632 / 901 |
| lung | 49% | 1032.25 | 285 / 578 | 42% | 9.60 | 485 / 1155 |
| blood vessel | 86% | 2419.81 | 1142 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 19.27 | 38 / 45 |
| breast | 52% | 1109.68 | 240 / 459 | 27% | 4.45 | 302 / 1118 |
| spleen | 68% | 1271.54 | 164 / 241 | 0% | 0 | 0 / 0 |
| adipose | 67% | 2079.05 | 806 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 55% | 5.49 | 16 / 29 |
| intestine | 29% | 641.20 | 282 / 966 | 16% | 5.04 | 82 / 527 |
| stomach | 28% | 579.24 | 100 / 359 | 15% | 4.12 | 42 / 286 |
| adrenal gland | 0% | 6.97 | 1 / 258 | 35% | 9.99 | 81 / 230 |
| liver | 1% | 12.29 | 2 / 226 | 24% | 5.72 | 98 / 406 |
| peripheral blood | 14% | 285.40 | 129 / 929 | 0% | 0 | 0 / 0 |
| heart | 7% | 137.67 | 62 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 6% | 0.83 | 5 / 80 |
| muscle | 0% | 3.45 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006468 | Biological process | protein phosphorylation |
| GO_0048013 | Biological process | ephrin receptor signaling pathway |
| GO_0007411 | Biological process | axon guidance |
| GO_0005829 | Cellular component | cytosol |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0038023 | Molecular function | signaling receptor activity |
| GO_0005003 | Molecular function | ephrin receptor activity |
| GO_0005005 | Molecular function | transmembrane-ephrin receptor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | EPHB6 |
| Protein name | EPH receptor B6 EPH receptor B6 (Ephrin type-B receptor 6) Ephrin type-B receptor 6 Ephrin type-B receptor 6 (HEP) (Tyrosine-protein kinase-defective receptor EPH-6) |
| Synonyms | |
| Description | FUNCTION: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. . |
| Accessions | ENST00000615824.1 ENST00000476059.2 A0A087WTE3 ENST00000422643.5 ENST00000633684.1 J3KQU5 ENST00000632037.1 ENST00000634148.1 ENST00000652003.1 ENST00000611578.4 A0A0G2JNC5 F8WCM8 ENST00000618483.4 ENST00000411471.6 ENST00000619012.4 A0A0J9YXG1 ENST00000631900.1 A0A0G2JNH7 O15197 ENST00000614832.4 A0A087WZL4 A0A087WYP8 ENST00000632242.1 |
