EPHA6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006468Biological processprotein phosphorylation
GO_0048013Biological processephrin receptor signaling pathway
GO_0008150Biological processbiological_process
GO_0007411Biological processaxon guidance
GO_0005654Cellular componentnucleoplasm
GO_0005886Cellular componentplasma membrane
GO_0030425Cellular componentdendrite
GO_0005005Molecular functiontransmembrane-ephrin receptor activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameEPHA6
Protein nameEPH receptor A6 (cDNA FLJ60941, highly similar to Ephrin type-A receptor 6 (EC2.7.10.1))
Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12)
EPH receptor A6
receptor protein-tyrosine kinase (EC 2.7.10.1)
SynonymsHEK12
EHK2
DescriptionFUNCTION: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). .

AccessionsH0Y8K5
ENST00000470610.6
H0Y9V0
A0A0B4J1T8
ENST00000477384.6
ENST00000502694.1 [Q9UF33-2]
ENST00000503760.5
J3KR66
B4DXM2
ENST00000514100.5 [Q9UF33-3]
Q9UF33
E7EU71
ENST00000389672.10
ENST00000506569.1
ENST00000506349.1