Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 12 studies | 53% ± 15% | |
GABAergic neuron | 10 studies | 56% ± 24% | |
astrocyte | 9 studies | 46% ± 23% | |
interneuron | 6 studies | 62% ± 23% | |
neuron | 5 studies | 27% ± 12% | |
endothelial cell | 4 studies | 44% ± 16% | |
granule cell | 4 studies | 64% ± 20% | |
oligodendrocyte precursor cell | 4 studies | 23% ± 10% | |
retinal ganglion cell | 4 studies | 85% ± 10% | |
GABAergic interneuron | 3 studies | 63% ± 6% | |
microglial cell | 3 studies | 49% ± 18% | |
GABAergic amacrine cell | 3 studies | 44% ± 12% | |
amacrine cell | 3 studies | 32% ± 3% | |
glycinergic amacrine cell | 3 studies | 30% ± 7% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 14 studies | 39% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 83% | 59.78 | 204 / 245 | 57% | 2.36 | 285 / 502 |
ovary | 98% | 254.84 | 176 / 180 | 34% | 0.87 | 146 / 430 |
brain | 90% | 151.35 | 2372 / 2642 | 19% | 0.44 | 136 / 705 |
thymus | 90% | 68.75 | 589 / 653 | 9% | 0.20 | 55 / 605 |
bladder | 90% | 105.62 | 19 / 21 | 4% | 0.09 | 19 / 504 |
esophagus | 77% | 45.84 | 1114 / 1445 | 10% | 0.20 | 18 / 183 |
uterus | 67% | 45.84 | 114 / 170 | 14% | 0.32 | 66 / 459 |
intestine | 73% | 215.03 | 705 / 966 | 1% | 0.02 | 7 / 527 |
breast | 45% | 26.04 | 207 / 459 | 6% | 0.24 | 72 / 1118 |
kidney | 21% | 8.78 | 19 / 89 | 29% | 0.80 | 264 / 901 |
blood vessel | 47% | 22.19 | 633 / 1335 | 0% | 0 | 0 / 0 |
stomach | 40% | 76.39 | 142 / 359 | 3% | 0.07 | 10 / 286 |
tonsil | 0% | 0 | 0 / 0 | 29% | 1.04 | 13 / 45 |
lung | 16% | 5.56 | 91 / 578 | 12% | 0.35 | 138 / 1155 |
heart | 26% | 11.24 | 227 / 861 | 0% | 0 | 0 / 0 |
adipose | 20% | 8.74 | 242 / 1204 | 0% | 0 | 0 / 0 |
adrenal gland | 1% | 0.23 | 2 / 258 | 19% | 0.54 | 44 / 230 |
pancreas | 7% | 2.15 | 24 / 328 | 7% | 0.16 | 12 / 178 |
liver | 0% | 0.19 | 1 / 226 | 9% | 0.28 | 36 / 406 |
skin | 4% | 1.34 | 70 / 1809 | 3% | 0.09 | 15 / 472 |
muscle | 0% | 0.29 | 3 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006468 | Biological process | protein phosphorylation |
GO_0048013 | Biological process | ephrin receptor signaling pathway |
GO_0008150 | Biological process | biological_process |
GO_0007411 | Biological process | axon guidance |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005886 | Cellular component | plasma membrane |
GO_0030425 | Cellular component | dendrite |
GO_0005005 | Molecular function | transmembrane-ephrin receptor activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
GO_0003674 | Molecular function | molecular_function |
Gene name | EPHA6 |
Protein name | EPH receptor A6 (cDNA FLJ60941, highly similar to Ephrin type-A receptor 6 (EC2.7.10.1)) Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12) EPH receptor A6 receptor protein-tyrosine kinase (EC 2.7.10.1) |
Synonyms | HEK12 EHK2 |
Description | FUNCTION: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). . |
Accessions | H0Y8K5 ENST00000470610.6 H0Y9V0 A0A0B4J1T8 ENST00000477384.6 ENST00000502694.1 [Q9UF33-2] ENST00000503760.5 J3KR66 B4DXM2 ENST00000514100.5 [Q9UF33-3] Q9UF33 E7EU71 ENST00000389672.10 ENST00000506569.1 ENST00000506349.1 |