EPB41L4B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010628Biological processpositive regulation of gene expression
GO_0031032Biological processactomyosin structure organization
GO_0045785Biological processpositive regulation of cell adhesion
GO_0010837Biological processregulation of keratinocyte proliferation
GO_0051549Biological processpositive regulation of keratinocyte migration
GO_0042060Biological processwound healing
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0045177Cellular componentapical part of cell
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005923Cellular componentbicellular tight junction
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0008092Molecular functioncytoskeletal protein binding

IV. Literature review

[source]
Gene nameEPB41L4B
Protein nameErythrocyte membrane protein band 4.1 like 4B, isoform CRA_a (cDNA: FLJ21596 fis, clone COL07110)
Erythrocyte membrane protein band 4.1 like 4B, isoform CRA_b (cDNA FLJ20381 fis, clone KAIA2329)
Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2)
SynonymshCG_1738334
EHM2
LULU2
DescriptionFUNCTION: Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (By similarity). Involved in the regulation of the circumferential actomyosin belt in epithelial cells . Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing . May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation . .

AccessionsQ9H329
Q9NX84
ENST00000374557.4 [Q9H329-2]
Q9H709
ENST00000374566.8 [Q9H329-1]