EML3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of EML3 at tissue level.

III. Associated gene sets

GO_1901673Biological processregulation of mitotic spindle assembly
GO_0051301Biological processcell division
GO_0007080Biological processmitotic metaphase chromosome alignment
GO_0000226Biological processmicrotubule cytoskeleton organization
GO_0005819Cellular componentspindle
GO_0005876Cellular componentspindle microtubule
GO_0030496Cellular componentmidbody
GO_1990498Cellular componentmitotic spindle microtubule
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0072686Cellular componentmitotic spindle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0008017Molecular functionmicrotubule binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameEML3
Protein nameEMAP like 3 (Echinoderm microtubule associated protein like 3, isoform CRA_c)
EMAP like 3 (Echinoderm microtubule associated protein like 3, isoform CRA_e)
EMAP like 3
Echinoderm microtubule-associated protein-like 3 (EMAP-3)
EMAP like 3 (Echinoderm microtubule associated protein like 3, isoform CRA_f)
SynonymshCG_20389
DescriptionFUNCTION: Regulates mitotic spindle assembly, microtubule (MT)-kinetochore attachment and chromosome separation via recruitment of HAUS augmin-like complex and TUBG1 to the existing MTs and promoting MT-based MT nucleation . Required for proper alignnment of chromosomes during metaphase . .

AccessionsH0Y3M3
ENST00000494176.6
ENST00000278845.8
E9PJV5
ENST00000466671.5
ENST00000394776.8
E9PSB4
B7WPE2
H7C355
ENST00000494448.5 [Q32P44-3]
Q32P44
G3V1D0
ENST00000529309.5 [Q32P44-2]
ENST00000466886.5
G3V195
ENST00000531557.5
ENST00000394773.7 [Q32P44-1]
ENST00000419857.1
ENST00000439994.5
C9J6V3