ELAC2 | OmnibusX

Name	Number of supported studies	Average coverage
brain	3 studies	20% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	5097.00	1445 / 1445	100%	34.58	183 / 183
ovary	100%	3066.25	180 / 180	100%	25.37	430 / 430
prostate	100%	4126.55	245 / 245	100%	35.26	502 / 502
stomach	100%	3512.62	359 / 359	100%	33.72	286 / 286
thymus	100%	3886.80	653 / 653	100%	36.12	605 / 605
lung	100%	3111.34	577 / 578	100%	30.29	1155 / 1155
breast	100%	4152.86	459 / 459	100%	35.45	1116 / 1118
intestine	100%	4316.67	966 / 966	100%	34.54	526 / 527
skin	100%	4372.09	1809 / 1809	100%	44.46	471 / 472
uterus	100%	3687.09	170 / 170	100%	39.24	458 / 459
kidney	100%	3430.98	89 / 89	100%	36.12	899 / 901
pancreas	100%	2336.65	327 / 328	100%	25.89	178 / 178
bladder	100%	4405.86	21 / 21	99%	34.62	501 / 504
brain	99%	2766.31	2625 / 2642	100%	40.57	705 / 705
liver	100%	3263.10	226 / 226	99%	23.43	403 / 406
adrenal gland	100%	6203.38	258 / 258	99%	25.29	227 / 230
adipose	100%	4117.27	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	42.43	80 / 80
lymph node	0%	0	0 / 0	100%	54.04	29 / 29
muscle	100%	5125.23	803 / 803	0%	0	0 / 0
spleen	100%	5375.62	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	38.19	45 / 45
ureter	0%	0	0 / 0	100%	14.09	1 / 1
blood vessel	100%	3843.75	1334 / 1335	0%	0	0 / 0
heart	99%	3786.51	849 / 861	0%	0	0 / 0
peripheral blood	85%	2303.73	787 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0090646	Biological process	mitochondrial tRNA processing
GO_0042780	Biological process	tRNA 3'-end processing
GO_1990180	Biological process	mitochondrial tRNA 3'-end processing
GO_0016078	Biological process	tRNA decay
GO_0005739	Cellular component	mitochondrion
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005759	Cellular component	mitochondrial matrix
GO_0042645	Cellular component	mitochondrial nucleoid
GO_0005634	Cellular component	nucleus
GO_0004521	Molecular function	RNA endonuclease activity
GO_0004549	Molecular function	tRNA-specific ribonuclease activity
GO_0042781	Molecular function	3'-tRNA processing endoribonuclease activity
GO_0046872	Molecular function	metal ion binding
GO_0003723	Molecular function	RNA binding

Gene name	ELAC2
Protein name	ElaC-like protein 2 isoform 2 ribonuclease Z (EC 3.1.26.11) Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Ribonuclease Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2) Zinc phosphodiesterase ELAC protein 2 (EC 3.1.26.11) (ElaC homolog protein 2) (Heredity prostate cancer protein 2) (Ribonuclease Z 2) (RNase Z 2) (tRNA 3 endonuclease 2) (tRNase Z 2) ElaC ribonuclease Z 2
Synonyms	HPC2 hCG_29734
Description	FUNCTION: Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA . Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly . .
Accessions	ENST00000584650.5 ENST00000476042.1 ENST00000581499.6 ENST00000609101.5 ENST00000578071.1 A0A0S2Z5M8 ENST00000583371.5 ENST00000338034.9 [Q9BQ52-1] ENST00000395962.6 ENST00000609757.5 A0A0S2Z5J8 ENST00000426905.7 [Q9BQ52-4] ENST00000580504.5 V9GYU5 V9GZ72 J3QLK4 J3QRS2 Q9BQ52 E7ES68 J3QL08 H7C2I4 G5E9D5 J3QQT1 V9GYS7 ENST00000446899.5

ELAC2 report