EFHB | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	15 studies	31% ± 10%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of EFHB at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	91%	153.18	2407 / 2642	78%	2.87	551 / 705
kidney	97%	139.11	86 / 89	42%	1.30	378 / 901
thymus	91%	72.91	596 / 653	34%	0.59	207 / 605
ovary	83%	85.88	149 / 180	35%	1.11	151 / 430
lung	89%	189.58	515 / 578	23%	0.78	269 / 1155
prostate	79%	55.09	193 / 245	31%	0.55	158 / 502
adrenal gland	81%	76.15	210 / 258	18%	0.32	42 / 230
skin	68%	47.21	1232 / 1809	30%	0.57	140 / 472
breast	72%	64.26	330 / 459	20%	0.36	223 / 1118
uterus	72%	74.54	122 / 170	13%	0.33	60 / 459
bladder	67%	48.10	14 / 21	8%	0.14	41 / 504
adipose	69%	62.18	828 / 1204	0%	0	0 / 0
spleen	66%	43.27	158 / 241	0%	0	0 / 0
intestine	60%	35.00	582 / 966	3%	0.05	15 / 527
blood vessel	61%	45.34	809 / 1335	0%	0	0 / 0
esophagus	55%	28.45	788 / 1445	5%	0.07	9 / 183
stomach	51%	25.09	184 / 359	2%	0.03	7 / 286
pancreas	34%	11.04	111 / 328	10%	0.18	18 / 178
eye	0%	0	0 / 0	39%	0.83	31 / 80
heart	36%	15.47	314 / 861	0%	0	0 / 0
peripheral blood	27%	9.56	251 / 929	0%	0	0 / 0
muscle	27%	9.22	214 / 803	0%	0	0 / 0
liver	16%	4.37	36 / 226	5%	0.14	19 / 406
lymph node	0%	0	0 / 0	3%	0.04	1 / 29
tonsil	0%	0	0 / 0	2%	0.04	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_2001256	Biological process	regulation of store-operated calcium entry
GO_0032091	Biological process	negative regulation of protein binding
GO_0006816	Biological process	calcium ion transport
GO_0070884	Biological process	regulation of calcineurin-NFAT signaling cascade
GO_0160111	Cellular component	axonemal A tubule inner sheath
GO_0005879	Cellular component	axonemal microtubule
GO_0061891	Molecular function	calcium ion sensor activity
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

Gene name	EFHB
Protein name	EF-hand domain-containing family member B (Cilia- and flagella-associated protein 21) EF-hand domain family member B
Synonyms	CFAP21
Description	FUNCTION: Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion and the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus . Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating . .
Accessions	ENST00000440022.1 H7C0U4 ENST00000295824.14 [Q8N7U6-1] Q8N7U6 H9KV82 ENST00000389256.8 ENST00000344838.8 [Q8N7U6-3]

EFHB report