EDC4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of EDC4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of EDC4 at tissue level.

III. Associated gene sets

GO_0031087Biological processdeadenylation-independent decapping of nuclear-transcribed mRNA
GO_0008150Biological processbiological_process
GO_0000932Cellular componentP-body
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameEDC4
Protein nameEnhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)
Enhancer of mRNA-decapping protein 4
Enhancer of mRNA decapping 4
SynonymsHEDLS
DescriptionFUNCTION: In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). .

AccessionsI3L2F4
A0A8B0RAT7
ENST00000573985.5
I3L0V0
ENST00000577105.1
ENST00000358933.10 [Q6P2E9-1]
I3L3M2
ENST00000575033.1
Q6P2E9