ECRG4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0090398Biological processcellular senescence
GO_0031145Biological processanaphase-promoting complex-dependent catabolic process
GO_0070314Biological processG1 to G0 transition
GO_0042127Biological processregulation of cell population proliferation
GO_0007417Biological processcentral nervous system development
GO_0016324Cellular componentapical plasma membrane
GO_0005615Cellular componentextracellular space
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameECRG4
Protein nameAugurin (Esophageal cancer-related gene 4 protein) (ECRG4)
ECRG4 augurin precursor
Alternative protein C2orf40
SynonymsUNQ761/PRO1508
C2orf40
DescriptionFUNCTION: Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity). .

AccessionsENST00000409944.5
Q9H1Z8
C9JRR0
ENST00000437659.1
B8ZZE5
L8E9F0
ENST00000238044.8