ECI1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006635Biological processfatty acid beta-oxidation
GO_0005759Cellular componentmitochondrial matrix
GO_0005739Cellular componentmitochondrion
GO_0016863Molecular functionintramolecular oxidoreductase activity, transposing C=C bonds
GO_0004165Molecular functiondelta(3)-delta(2)-enoyl-CoA isomerase activity

IV. Literature review

[source]
Gene nameECI1
Protein nameEnoyl-CoA delta isomerase 1
DCI protein (Dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase), isoform CRA_a) (Enoyl-CoA delta isomerase 1)
Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase)
SynonymshCG_41028
DCI
DescriptionFUNCTION: Key enzyme of fatty acid beta-oxidation (Probable). Able to isomerize both 3-cis (3Z) and 3-trans (3E) double bonds into the 2-trans (2E) form in a range of enoyl-CoA species, with a preference for (3Z)-enoyl-CoAs over (3E)-enoyl-CoAs (By similarity). The catalytic efficiency of this enzyme is not affected by the fatty acyl chain length (By similarity). .

AccessionsENST00000562238.5 [P42126-2]
Q96DC0
ENST00000570258.5
H3BS70
ENST00000566379.1
ENST00000301729.9 [P42126-1]
P42126