Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 4 studies | 23% ± 6% | |
epithelial cell | 4 studies | 28% ± 11% | |
oligodendrocyte | 4 studies | 19% ± 2% | |
GABAergic neuron | 3 studies | 36% ± 7% | |
glutamatergic neuron | 3 studies | 45% ± 5% | |
astrocyte | 3 studies | 24% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 32% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1960.51 | 459 / 459 | 100% | 42.98 | 1118 / 1118 |
esophagus | 100% | 1535.55 | 1445 / 1445 | 100% | 33.65 | 183 / 183 |
intestine | 100% | 1545.99 | 966 / 966 | 100% | 27.02 | 527 / 527 |
lung | 100% | 1498.00 | 578 / 578 | 100% | 29.42 | 1155 / 1155 |
ovary | 100% | 1753.52 | 180 / 180 | 100% | 33.30 | 430 / 430 |
bladder | 100% | 1709.05 | 21 / 21 | 100% | 27.47 | 503 / 504 |
prostate | 100% | 1809.94 | 245 / 245 | 100% | 32.97 | 501 / 502 |
skin | 100% | 1989.86 | 1809 / 1809 | 100% | 30.66 | 471 / 472 |
pancreas | 100% | 867.17 | 327 / 328 | 100% | 26.52 | 178 / 178 |
thymus | 100% | 1777.40 | 653 / 653 | 100% | 32.93 | 603 / 605 |
stomach | 100% | 1231.85 | 359 / 359 | 100% | 29.59 | 285 / 286 |
uterus | 100% | 1818.54 | 170 / 170 | 100% | 28.93 | 457 / 459 |
brain | 100% | 1221.36 | 2629 / 2642 | 100% | 24.80 | 705 / 705 |
liver | 100% | 846.69 | 226 / 226 | 99% | 19.96 | 403 / 406 |
kidney | 100% | 1347.29 | 89 / 89 | 99% | 24.28 | 891 / 901 |
adrenal gland | 100% | 1716.95 | 258 / 258 | 99% | 29.98 | 227 / 230 |
adipose | 100% | 1862.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1856.00 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 28.07 | 29 / 29 |
spleen | 100% | 1565.78 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 25.45 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.57 | 1 / 1 |
muscle | 100% | 965.28 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1022.83 | 844 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 98% | 1367.01 | 906 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 25.15 | 78 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_2000045 | Biological process | regulation of G1/S transition of mitotic cell cycle |
GO_0008380 | Biological process | RNA splicing |
GO_0006397 | Biological process | mRNA processing |
GO_0048144 | Biological process | fibroblast proliferation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0035035 | Molecular function | histone acetyltransferase binding |
Gene name | ECD |
Protein name | Ecdysoneless cell cycle regulator Protein ecdysoneless homolog (Human suppressor of GCR two) (hSGT1) |
Synonyms | |
Description | FUNCTION: Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP . May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes . Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins . The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex . May play a role in regulation of pre-mRNA splicing . . |
Accessions | ENST00000453402.5 C9JGV1 ENST00000454759.6 [O95905-2] ENST00000494307.1 O95905 S4R458 ENST00000372979.9 [O95905-1] ENST00000430082.6 [O95905-3] F2Z2R1 C9J316 ENST00000484976.6 ENST00000413026.1 |