DYNLRB2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007018Biological processmicrotubule-based movement
GO_0097542Cellular componentciliary tip
GO_0005813Cellular componentcentrosome
GO_0005929Cellular componentcilium
GO_0005868Cellular componentcytoplasmic dynein complex
GO_0005874Cellular componentmicrotubule
GO_0005737Cellular componentcytoplasm
GO_0045505Molecular functiondynein intermediate chain binding
GO_0003777Molecular functionmicrotubule motor activity

IV. Literature review

[source]
Gene nameDYNLRB2
Protein nameDynein light chain roadblock-type 2
Dynein light chain roadblock
DYNLRB2 protein (Dynein light chain roadblock-type 2)
Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2)
SynonymsDNLC2B
DNCL2B
hCG_16745
ROBLD2
DescriptionFUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. .

AccessionsQ7Z4M1
H3BNG9
H3BPA0
ENST00000562982.5
ENST00000561880.1
ENST00000338542.9
ENST00000568035.5
A0A140VJH9
H3BQI1
Q8TF09
ENST00000305904.11