Insufficient scRNA-seq data for expression of DUSP13B at single-cell level.
Insufficient scRNA-seq data for expression of DUSP13B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
muscle | 100% | 10157.24 | 803 / 803 | 0% | 0 | 0 / 0 |
heart | 94% | 518.05 | 808 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 67% | 251.12 | 624 / 929 | 0% | 0 | 0 / 0 |
thymus | 1% | 4.09 | 7 / 653 | 36% | 1.19 | 218 / 605 |
lung | 6% | 8.06 | 35 / 578 | 28% | 2.09 | 323 / 1155 |
esophagus | 15% | 18.01 | 211 / 1445 | 11% | 0.27 | 21 / 183 |
breast | 2% | 5.69 | 11 / 459 | 21% | 1.07 | 230 / 1118 |
tonsil | 0% | 0 | 0 / 0 | 20% | 0.98 | 9 / 45 |
prostate | 9% | 50.63 | 21 / 245 | 5% | 0.68 | 27 / 502 |
lymph node | 0% | 0 | 0 / 0 | 14% | 0.79 | 4 / 29 |
uterus | 1% | 0.94 | 1 / 170 | 12% | 1.62 | 56 / 459 |
spleen | 12% | 18.25 | 29 / 241 | 0% | 0 | 0 / 0 |
bladder | 0% | 0 | 0 / 21 | 8% | 0.44 | 40 / 504 |
liver | 0% | 0 | 0 / 226 | 6% | 0.38 | 26 / 406 |
skin | 4% | 13.93 | 78 / 1809 | 1% | 0.10 | 6 / 472 |
adrenal gland | 0% | 0 | 0 / 258 | 5% | 0.36 | 12 / 230 |
brain | 0% | 0.45 | 12 / 2642 | 4% | 0.09 | 30 / 705 |
pancreas | 0% | 0 | 0 / 328 | 3% | 0.07 | 6 / 178 |
ovary | 0% | 0 | 0 / 180 | 3% | 0.10 | 13 / 430 |
kidney | 1% | 0.81 | 1 / 89 | 2% | 0.04 | 17 / 901 |
stomach | 0% | 0.22 | 1 / 359 | 1% | 0.03 | 4 / 286 |
intestine | 0% | 0.10 | 1 / 966 | 2% | 0.03 | 8 / 527 |
blood vessel | 1% | 5.02 | 16 / 1335 | 0% | 0 | 0 / 0 |
adipose | 1% | 1.50 | 11 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0043409 | Biological process | negative regulation of MAPK cascade |
GO_0051321 | Biological process | meiotic cell cycle |
GO_0007283 | Biological process | spermatogenesis |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0016311 | Biological process | dephosphorylation |
GO_0005737 | Cellular component | cytoplasm |
GO_0016791 | Molecular function | phosphatase activity |
GO_0008138 | Molecular function | protein tyrosine/serine/threonine phosphatase activity |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0005515 | Molecular function | protein binding |
GO_0033549 | Molecular function | MAP kinase phosphatase activity |
GO_0004725 | Molecular function | protein tyrosine phosphatase activity |
Gene name | DUSP13B |
Protein name | protein-serine/threonine phosphatase (EC 3.1.3.16) Dual specificity protein phosphatase 13B (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase SKRP4) (Testis- and skeletal-muscle-specific DSP) Dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48) |
Synonyms | TMDP SKRP4 DUSP13 hCG_22509 |
Description | FUNCTION: Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro . Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro . . FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. . FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. . FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. . |
Accessions | ENST00000605915.5 U3KQA1 A0A9L9PXN7 ENST00000707122.1 ENST00000372700.8 [Q9UII6-4] U3KQB7 A0A9L9PYL3 ENST00000478873.7 [Q9UII6-5] Q9UII6 ENST00000464872.5 ENST00000473072.3 E9PSD4 ENST00000707120.1 ENST00000707121.1 [Q9UII6-1] ENST00000472493.6 [Q9UII6-1] |