DUSP13B report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DUSP13B at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DUSP13B at tissue level.

III. Associated gene sets

GO_0043409Biological processnegative regulation of MAPK cascade
GO_0051321Biological processmeiotic cell cycle
GO_0007283Biological processspermatogenesis
GO_0006470Biological processprotein dephosphorylation
GO_0016311Biological processdephosphorylation
GO_0005737Cellular componentcytoplasm
GO_0016791Molecular functionphosphatase activity
GO_0008138Molecular functionprotein tyrosine/serine/threonine phosphatase activity
GO_0017018Molecular functionmyosin phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0033549Molecular functionMAP kinase phosphatase activity
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene nameDUSP13B
Protein nameprotein-serine/threonine phosphatase (EC 3.1.3.16)
Dual specificity protein phosphatase 13B (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase SKRP4) (Testis- and skeletal-muscle-specific DSP)
Dual specificity protein phosphatase (EC 3.1.3.16) (EC 3.1.3.48)
SynonymsTMDP
SKRP4
DUSP13
hCG_22509
DescriptionFUNCTION: Dual specificity phosphatase that dephosphorylates MAPK8/JNK and MAPK14/p38, but not MAPK1/ERK2, in vitro . Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues, with similar specific activities in vitro . .

FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. .

FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. .

FUNCTION: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. .

AccessionsENST00000605915.5
U3KQA1
A0A9L9PXN7
ENST00000707122.1
ENST00000372700.8 [Q9UII6-4]
U3KQB7
A0A9L9PYL3
ENST00000478873.7 [Q9UII6-5]
Q9UII6
ENST00000464872.5
ENST00000473072.3
E9PSD4
ENST00000707120.1
ENST00000707121.1 [Q9UII6-1]
ENST00000472493.6 [Q9UII6-1]