DRGX report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DRGX at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DRGX at tissue level.

III. Associated gene sets

GO_0021516Biological processdorsal spinal cord development
GO_0021559Biological processtrigeminal nerve development
GO_0050954Biological processsensory perception of mechanical stimulus
GO_0016048Biological processdetection of temperature stimulus
GO_0001764Biological processneuron migration
GO_0009593Biological processdetection of chemical stimulus
GO_0007411Biological processaxon guidance
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameDRGX
Protein nameDorsal root ganglia homeobox protein (Paired-related homeobox protein-like 1)
SynonymsPRRXL1
DescriptionFUNCTION: Transcription factor required for the formation of correct projections from nociceptive sensory neurons to the dorsal horn of the spinal cord and normal perception of pain. .

AccessionsA6NNA5
ENST00000374139.8