Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 10 studies | 21% ± 5% | |
| epithelial cell | 6 studies | 31% ± 12% | |
| fibroblast | 5 studies | 22% ± 7% | |
| ciliated cell | 4 studies | 24% ± 7% | |
| abnormal cell | 4 studies | 21% ± 6% | |
| GABAergic neuron | 4 studies | 33% ± 10% | |
| glutamatergic neuron | 4 studies | 40% ± 9% | |
| basal cell | 4 studies | 25% ± 10% | |
| astrocyte | 4 studies | 29% ± 8% | |
| oligodendrocyte | 4 studies | 23% ± 4% | |
| natural killer cell | 4 studies | 19% ± 3% | |
| CD4-positive, alpha-beta T cell | 3 studies | 20% ± 4% | |
| hematopoietic precursor cell | 3 studies | 25% ± 6% | |
| non-classical monocyte | 3 studies | 20% ± 3% | |
| retinal bipolar neuron | 3 studies | 21% ± 5% | |
| erythroblast | 3 studies | 31% ± 12% | |
| macrophage | 3 studies | 19% ± 2% | |
| dendritic cell | 3 studies | 28% ± 5% | |
| adipocyte | 3 studies | 19% ± 4% | |
| interneuron | 3 studies | 37% ± 14% | |
| neuron | 3 studies | 30% ± 2% | |
| plasmacytoid dendritic cell | 3 studies | 22% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 100% | 2632.52 | 459 / 459 | 100% | 98.56 | 1118 / 1118 |
| ovary | 100% | 2326.39 | 180 / 180 | 100% | 82.82 | 430 / 430 |
| pancreas | 100% | 1553.92 | 328 / 328 | 100% | 64.09 | 178 / 178 |
| prostate | 100% | 2018.83 | 245 / 245 | 100% | 81.71 | 502 / 502 |
| stomach | 100% | 1705.37 | 359 / 359 | 100% | 77.33 | 286 / 286 |
| thymus | 100% | 2087.65 | 653 / 653 | 100% | 86.98 | 605 / 605 |
| esophagus | 100% | 1976.65 | 1444 / 1445 | 100% | 70.15 | 183 / 183 |
| kidney | 100% | 1835.58 | 89 / 89 | 100% | 67.02 | 900 / 901 |
| intestine | 100% | 1964.91 | 966 / 966 | 100% | 78.51 | 526 / 527 |
| skin | 100% | 2648.60 | 1809 / 1809 | 100% | 101.84 | 471 / 472 |
| uterus | 100% | 2178.46 | 170 / 170 | 100% | 96.13 | 458 / 459 |
| bladder | 100% | 2205.81 | 21 / 21 | 100% | 89.63 | 502 / 504 |
| brain | 100% | 1875.78 | 2631 / 2642 | 100% | 81.89 | 705 / 705 |
| liver | 100% | 1314.27 | 225 / 226 | 100% | 63.16 | 406 / 406 |
| lung | 99% | 1728.48 | 575 / 578 | 100% | 90.24 | 1155 / 1155 |
| adrenal gland | 100% | 2885.35 | 258 / 258 | 98% | 52.98 | 226 / 230 |
| adipose | 100% | 2520.72 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 2110.05 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 77.78 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 113.72 | 29 / 29 |
| muscle | 100% | 4928.41 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1678.17 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 93.52 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 57.09 | 1 / 1 |
| heart | 98% | 2185.38 | 843 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 91% | 1458.63 | 847 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1901673 | Biological process | regulation of mitotic spindle assembly |
| GO_0031116 | Biological process | positive regulation of microtubule polymerization |
| GO_0002181 | Biological process | cytoplasmic translation |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005525 | Molecular function | GTP binding |
| GO_0030955 | Molecular function | potassium ion binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0008017 | Molecular function | microtubule binding |
| GO_0003924 | Molecular function | GTPase activity |
| Gene name | DRG1 |
| Protein name | Developmentally regulated GTP binding protein 1 Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3) (Translation factor GTPase DRG1) (TRAFAC GTPase DRG1) (EC 3.6.5.-) Developmentally regulated GTP binding protein 1 (SFI1 centrin binding protein) |
| Synonyms | NEDD3 SFI1 |
| Description | FUNCTION: Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP . Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions . When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation . Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions . . |
| Accessions | Q9Y295 F8WEE0 ENST00000416465.5 ENST00000548143.1 ENST00000331457.9 F8WBU4 ENST00000629688.1 H0YI06 ENST00000411518.5 |