DRC7 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DRC7 at tissue level.

III. Associated gene sets

GO_0007288Biological processsperm axoneme assembly
GO_0007283Biological processspermatogenesis
GO_0030317Biological processflagellated sperm motility
GO_0031514Cellular componentmotile cilium
GO_0005856Cellular componentcytoskeleton
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDRC7
Protein nameDynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog)
Dynein regulatory complex subunit 7
SynonymsCCDC135
C16orf50
DescriptionFUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Involved in the regulation of flagellar motility (By similarity). Essential for male fertility, sperm head morphogenesis and sperm flagellum formation (By similarity). .

AccessionsENST00000563126.5
H3BUK0
H3BRR8
H3BN79
ENST00000564297.5
ENST00000569375.5
ENST00000360716.8 [Q8IY82-1]
ENST00000569167.1
H3BQY5
ENST00000562250.1
ENST00000564132.1
ENST00000394337.8 [Q8IY82-1]
H3BRX1
H3BRN2
ENST00000336825.12 [Q8IY82-2]
Q8IY82