Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 12 studies | 29% ± 8% |
Insufficient scRNA-seq data for expression of DRC7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 97% | 67.81 | 86 / 89 | 35% | 2.37 | 318 / 901 |
brain | 86% | 95.01 | 2262 / 2642 | 30% | 1.18 | 210 / 705 |
pancreas | 91% | 29.67 | 297 / 328 | 16% | 0.49 | 28 / 178 |
lung | 84% | 248.10 | 488 / 578 | 15% | 0.56 | 174 / 1155 |
peripheral blood | 79% | 69.79 | 736 / 929 | 0% | 0 | 0 / 0 |
ovary | 33% | 7.56 | 60 / 180 | 37% | 1.23 | 159 / 430 |
liver | 50% | 13.49 | 114 / 226 | 18% | 0.35 | 72 / 406 |
uterus | 38% | 57.58 | 65 / 170 | 12% | 0.85 | 53 / 459 |
thymus | 47% | 12.02 | 305 / 653 | 1% | 0.02 | 5 / 605 |
spleen | 47% | 23.78 | 114 / 241 | 0% | 0 | 0 / 0 |
prostate | 20% | 7.21 | 48 / 245 | 6% | 0.17 | 29 / 502 |
adipose | 15% | 3.00 | 185 / 1204 | 0% | 0 | 0 / 0 |
stomach | 11% | 1.60 | 38 / 359 | 2% | 0.03 | 6 / 286 |
breast | 6% | 2.80 | 26 / 459 | 4% | 0.10 | 47 / 1118 |
intestine | 6% | 1.18 | 58 / 966 | 3% | 0.06 | 14 / 527 |
bladder | 5% | 0.81 | 1 / 21 | 2% | 0.04 | 10 / 504 |
adrenal gland | 5% | 0.67 | 12 / 258 | 1% | 0.02 | 2 / 230 |
esophagus | 2% | 0.73 | 27 / 1445 | 2% | 0.03 | 4 / 183 |
skin | 2% | 0.56 | 28 / 1809 | 1% | 0.03 | 5 / 472 |
heart | 2% | 0.38 | 19 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 2% | 0.39 | 29 / 1335 | 0% | 0 | 0 / 0 |
muscle | 1% | 0.80 | 5 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007288 | Biological process | sperm axoneme assembly |
GO_0007283 | Biological process | spermatogenesis |
GO_0030317 | Biological process | flagellated sperm motility |
GO_0031514 | Cellular component | motile cilium |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | DRC7 |
Protein name | Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog) Dynein regulatory complex subunit 7 |
Synonyms | CCDC135 C16orf50 |
Description | FUNCTION: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Involved in the regulation of flagellar motility (By similarity). Essential for male fertility, sperm head morphogenesis and sperm flagellum formation (By similarity). . |
Accessions | ENST00000563126.5 H3BUK0 H3BRR8 H3BN79 ENST00000564297.5 ENST00000569375.5 ENST00000360716.8 [Q8IY82-1] ENST00000569167.1 H3BQY5 ENST00000562250.1 ENST00000564132.1 ENST00000394337.8 [Q8IY82-1] H3BRX1 H3BRN2 ENST00000336825.12 [Q8IY82-2] Q8IY82 |