DPY19L1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006486Biological processprotein glycosylation
GO_0018406Biological processprotein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan
GO_0005637Cellular componentnuclear inner membrane
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0000030Molecular functionmannosyltransferase activity

IV. Literature review

[source]
Gene nameDPY19L1
Protein nameDpy-19 like C-mannosyltransferase 1
Protein C-mannosyl-transferase DPY19L1 (EC 2.4.1.-) (Dpy-19-like protein 1) (Protein dpy-19 homolog 1)
SynonymsKIAA0877
GA0500
DescriptionFUNCTION: C-mannosyltransferase that mediates the C-mannosylation tryptophan residues on target proteins. The reaction occurs on the luminal side of the endoplasmic reticulum and involves the transfer of a mannose unit from a dolichylphosphate mannose (Dol-P-Man) donor to an acceptor protein containing a WxxW consensus sequence (By similarity). C-mannosylates the first two tryptophans in the WxxWxxWxxC motif in thrombospondin (TSP) type-1 of UNC5A (By similarity). Regulates neurite extension during development (By similarity). .

AccessionsA0A8I5KUQ5
H7C3M5
ENST00000638088.2
H7C1I8
ENST00000685246.1
ENST00000446375.1
ENST00000690666.1
A0A8I5KSD1
A0A8J9BZN9
ENST00000690503.1
ENST00000612226.2
A0A8I5KPK9
ENST00000310974.8 [Q2PZI1-1]
A0A1B0GW05
Q2PZI1
ENST00000428054.1