I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 24% ± 7% | |
| dendritic cell | 3 studies | 24% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 5 studies | 24% ± 7% | |
| dendritic cell | 3 studies | 24% ± 2% |
Insufficient scRNA-seq data for expression of DPP3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1731.11 | 1443 / 1445 | 100% | 52.11 | 183 / 183 |
| intestine | 100% | 2103.16 | 966 / 966 | 100% | 63.09 | 525 / 527 |
| uterus | 100% | 1191.22 | 170 / 170 | 100% | 46.34 | 457 / 459 |
| ovary | 99% | 783.21 | 179 / 180 | 100% | 49.38 | 430 / 430 |
| prostate | 100% | 1920.86 | 245 / 245 | 99% | 41.05 | 499 / 502 |
| breast | 100% | 1456.29 | 459 / 459 | 99% | 54.79 | 1110 / 1118 |
| lung | 99% | 1832.29 | 575 / 578 | 100% | 52.20 | 1151 / 1155 |
| pancreas | 100% | 1249.28 | 327 / 328 | 99% | 42.73 | 177 / 178 |
| bladder | 100% | 1727.71 | 21 / 21 | 99% | 58.03 | 499 / 504 |
| stomach | 100% | 1739.98 | 359 / 359 | 99% | 57.95 | 283 / 286 |
| skin | 100% | 2017.82 | 1809 / 1809 | 99% | 40.46 | 467 / 472 |
| thymus | 100% | 1624.70 | 651 / 653 | 99% | 26.22 | 596 / 605 |
| brain | 98% | 866.15 | 2581 / 2642 | 100% | 28.75 | 704 / 705 |
| liver | 100% | 1312.35 | 225 / 226 | 98% | 25.67 | 397 / 406 |
| kidney | 100% | 2001.56 | 89 / 89 | 97% | 26.76 | 876 / 901 |
| adrenal gland | 100% | 2156.85 | 258 / 258 | 87% | 19.59 | 201 / 230 |
| adipose | 100% | 1431.42 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 64.52 | 29 / 29 |
| spleen | 100% | 1921.74 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 50.13 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 40.05 | 1 / 1 |
| muscle | 100% | 1923.77 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1274.22 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 98% | 28.39 | 78 / 80 |
| peripheral blood | 97% | 1969.30 | 900 / 929 | 0% | 0 | 0 / 0 |
| heart | 92% | 820.02 | 788 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006508 | Biological process | proteolysis |
| GO_0030163 | Biological process | protein catabolic process |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0008239 | Molecular function | dipeptidyl-peptidase activity |
| GO_0008235 | Molecular function | metalloexopeptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| GO_0004177 | Molecular function | aminopeptidase activity |
| Gene name | DPP3 |
| Protein name | Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl peptidase III) Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) Dipeptidyl peptidase 3 |
| Synonyms | hCG_2016942 |
| Description | FUNCTION: Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin . Also cleaves Arg-Arg-beta-naphthylamide (in vitro) . . |
| Accessions | E9PPK9 ENST00000532677.5 ENST00000531354.2 G3V1D3 Q9NY33 E9PQ14 ENST00000531314.1 E9PQF2 G3V180 ENST00000531863 E9PNX5 ENST00000532019.5 ENST00000530165.5 [Q9NY33-4] ENST00000533725.5 ENST00000526515.5 ENST00000531863.6 [Q9NY33-1] ENST00000541961.5 [Q9NY33-1] E9PKK8 |
