DPAGT1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DPAGT1 at tissue level.

III. Associated gene sets

GO_0006047Biological processUDP-N-acetylglucosamine metabolic process
GO_0006487Biological processprotein N-linked glycosylation
GO_0006488Biological processdolichol-linked oligosaccharide biosynthetic process
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0016020Cellular componentmembrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0003975Molecular functionUDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity
GO_0016757Molecular functionglycosyltransferase activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0003976Molecular functionUDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameDPAGT1
Protein nameUDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (G1PT) (GPT) (N-acetylglucosamine-1-phosphate transferase)
Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15) (GlcNAc-1-P transferase) (N-acetylglucosamine-1-phosphate transferase)
SynonymsDPAGT2
DescriptionFUNCTION: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. .

FUNCTION: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. .

FUNCTION: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. .

FUNCTION: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. .

AccessionsENST00000640102.1
ENST00000684142.1
F8WE55
ENST00000354202.9 [Q9H3H5-1]
ENST00000684499.1
ENST00000636404.1
H7C2L6
A0A1W2PPC6
ENST00000409993.6 [Q9H3H5-1]
ENST00000638850.1
A0A804HJ22
ENST00000684682.1
ENST00000683143.1
A0A1W2PQH0
A0A1B0GV58
A0A1W2PRR6
A0A804HHX1
ENST00000684255.1
ENST00000682326.1
ENST00000682791.1
ENST00000442480.1
ENST00000640747.1
A0A804HJ11
A0A804HI18
A0A804HL46
ENST00000684345.1
ENST00000392834.7
A0A1W2PQD1
ENST00000414373.5
A0A804HIP7
A0A804HKZ3
ENST00000682946.1
ENST00000639704.1
ENST00000682811.1
F8W681
Q9H3H5
ENST00000682232.1