DONSON report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007095Biological processmitotic G2 DNA damage checkpoint signaling
GO_0033314Biological processmitotic DNA replication checkpoint signaling
GO_0031297Biological processreplication fork processing
GO_0033260Biological processnuclear DNA replication
GO_0006260Biological processDNA replication
GO_0000077Biological processDNA damage checkpoint signaling
GO_0005657Cellular componentreplication fork
GO_0030894Cellular componentreplisome
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDONSON
Protein nameDNA replication fork stabilization factor DONSON
Protein downstream neighbor of Son (B17)
SynonymsC21orf60
DescriptionFUNCTION: Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability. .

AccessionsENST00000444517.5
V9GY84
ENST00000442660.5
H7C1C1
ENST00000303113.10
F8W8A5
ENST00000432378.5
ENST00000457359.5
H7C006
ENST00000440810.1
F8WC22
ENST00000453626.5
ENST00000417871.5
ENST00000437395.5
ENST00000303071.10 [Q9NYP3-1]
C9JSP0
C9J4K5
Q9NYP3
F8WD19
H7C304
ENST00000439593.1
H7C1M7