DOLK report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DOLK at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DOLK at tissue level.

III. Associated gene sets

GO_0006489Biological processdolichyl diphosphate biosynthetic process
GO_0043048Biological processdolichyl monophosphate biosynthetic process
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0004168Molecular functiondolichol kinase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDOLK
Protein nameDolichol kinase (EC 2.7.1.108) (Transmembrane protein 15)
dolichol kinase (EC 2.7.1.108)
SynonymsUNQ2422/PRO4980
KIAA1094
TMEM15
hCG_30591
DescriptionFUNCTION: Catalyzes CTP-mediated phosphorylation of dolichol, the terminal step in de novo dolichyl monophosphate (Dol-P) biosynthesis . Dol-P is a lipid carrier essential for the synthesis of N-linked and O-linked oligosaccharides and for GPI anchors . .

AccessionsA0A0S2Z597
ENST00000372586.4
Q9UPQ8
A0A0S2Z5Y1