DNAH8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DNAH8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DNAH8 at tissue level.

III. Associated gene sets

GO_0060294Biological processcilium movement involved in cell motility
GO_0036158Biological processouter dynein arm assembly
GO_0060285Biological processcilium-dependent cell motility
GO_0005930Cellular componentaxoneme
GO_0005858Cellular componentaxonemal dynein complex
GO_0036126Cellular componentsperm flagellum
GO_0036157Cellular componentouter dynein arm
GO_0005874Cellular componentmicrotubule
GO_0051959Molecular functiondynein light intermediate chain binding
GO_0008569Molecular functionminus-end-directed microtubule motor activity
GO_0045505Molecular functiondynein intermediate chain binding
GO_0003777Molecular functionmicrotubule motor activity
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameDNAH8
Protein nameDynein axonemal heavy chain 8
Axonemal dynein heavy chain 8 isoform 2 (Axonemal dynein heavy chain 8 isoform 3) (Dynein axonemal heavy chain 8)
Truncated axonemal dynein heavy chain 8 isoform 4
Dynein axonemal heavy chain 8 (Axonemal beta dynein heavy chain 8) (Ciliary dynein heavy chain 8)
Synonyms
DescriptionFUNCTION: Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. .

AccessionsENST00000394393.3
Q8IU65
H3BLZ4
Q96JB1
H0Y7V4
ENST00000373278.8
ENST00000449981.6
Q8IZR0
ENST00000359357.7 [Q96JB1-1]
A0A075B6F3
ENST00000327475.11