DNAH12 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DNAH12 at tissue level.

III. Associated gene sets

GO_0007018Biological processmicrotubule-based movement
GO_0005858Cellular componentaxonemal dynein complex
GO_0005874Cellular componentmicrotubule
GO_0051959Molecular functiondynein light intermediate chain binding
GO_0008569Molecular functionminus-end-directed microtubule motor activity
GO_0045505Molecular functiondynein intermediate chain binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameDNAH12
Protein nameDynein axonemal heavy chain 12
Dynein heavy chain 12, axonemal
Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2)
SynonymsDNAH7L
DLP12
HDHC3
HL19
DHC3
DNAH12L
DNAHC3
DNHD2
DescriptionFUNCTION: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). .

AccessionsENST00000466540.2
ENST00000311202.7 [Q6ZR08-4]
ENST00000389536
Q6ZR08
ENST00000494758.5
ENST00000351747.6 [Q6ZR08-1]
E9PG32
H7C5N3
ENST00000495027.6
J3QTM1
H7C5S4