Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 19 studies | 73% ± 20% | |
| deuterosomal cell | 4 studies | 43% ± 2% | |
| epithelial cell | 3 studies | 26% ± 8% | |
| glutamatergic neuron | 3 studies | 23% ± 6% | |
| astrocyte | 3 studies | 32% ± 22% | |
| interneuron | 3 studies | 21% ± 6% |
Insufficient scRNA-seq data for expression of DNAH12 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 1030.64 | 571 / 578 | 13% | 0.52 | 154 / 1155 |
| pancreas | 100% | 92.45 | 328 / 328 | 3% | 0.05 | 6 / 178 |
| adrenal gland | 99% | 72.60 | 256 / 258 | 4% | 0.11 | 9 / 230 |
| ovary | 93% | 48.38 | 168 / 180 | 9% | 0.29 | 37 / 430 |
| brain | 95% | 135.08 | 2523 / 2642 | 4% | 0.10 | 30 / 705 |
| prostate | 92% | 34.22 | 226 / 245 | 2% | 0.04 | 8 / 502 |
| thymus | 92% | 34.73 | 601 / 653 | 0% | 0 | 0 / 605 |
| breast | 85% | 38.68 | 389 / 459 | 6% | 0.13 | 65 / 1118 |
| spleen | 84% | 20.67 | 203 / 241 | 0% | 0 | 0 / 0 |
| uterus | 77% | 182.68 | 131 / 170 | 3% | 0.14 | 16 / 459 |
| kidney | 79% | 24.89 | 70 / 89 | 0% | 0.01 | 4 / 901 |
| liver | 73% | 17.63 | 166 / 226 | 5% | 0.10 | 22 / 406 |
| stomach | 72% | 16.12 | 260 / 359 | 5% | 0.11 | 13 / 286 |
| adipose | 75% | 20.65 | 903 / 1204 | 0% | 0 | 0 / 0 |
| skin | 74% | 20.05 | 1334 / 1809 | 0% | 0.01 | 1 / 472 |
| bladder | 71% | 16.48 | 15 / 21 | 2% | 0.04 | 8 / 504 |
| intestine | 68% | 15.18 | 655 / 966 | 1% | 0.02 | 7 / 527 |
| muscle | 63% | 15.04 | 502 / 803 | 0% | 0 | 0 / 0 |
| esophagus | 54% | 10.68 | 784 / 1445 | 3% | 0.08 | 6 / 183 |
| blood vessel | 43% | 8.38 | 577 / 1335 | 0% | 0 | 0 / 0 |
| heart | 28% | 4.77 | 245 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 19% | 5.62 | 178 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007018 | Biological process | microtubule-based movement |
| GO_0005858 | Cellular component | axonemal dynein complex |
| GO_0005874 | Cellular component | microtubule |
| GO_0051959 | Molecular function | dynein light intermediate chain binding |
| GO_0008569 | Molecular function | minus-end-directed microtubule motor activity |
| GO_0045505 | Molecular function | dynein intermediate chain binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | DNAH12 |
| Protein name | Dynein axonemal heavy chain 12 Dynein heavy chain 12, axonemal Dynein axonemal heavy chain 12 (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12) (Dynein axonemal heavy chain 7-like) (Dynein heavy chain domain-containing protein 2) |
| Synonyms | DNAH7L DLP12 HDHC3 HL19 DHC3 DNAH12L DNAHC3 DNHD2 |
| Description | FUNCTION: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). . |
| Accessions | ENST00000466540.2 ENST00000311202.7 [Q6ZR08-4] ENST00000389536 Q6ZR08 ENST00000494758.5 ENST00000351747.6 [Q6ZR08-1] E9PG32 H7C5N3 ENST00000495027.6 J3QTM1 H7C5S4 |