I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 11 studies | 32% ± 10% | |
| GABAergic neuron | 3 studies | 22% ± 3% | |
| glutamatergic neuron | 3 studies | 29% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 11 studies | 32% ± 10% | |
| GABAergic neuron | 3 studies | 22% ± 3% | |
| glutamatergic neuron | 3 studies | 29% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2648.51 | 245 / 245 | 95% | 3.17 | 479 / 502 |
| brain | 97% | 2082.80 | 2569 / 2642 | 98% | 4.81 | 689 / 705 |
| thymus | 100% | 2413.70 | 652 / 653 | 94% | 2.75 | 567 / 605 |
| pancreas | 100% | 1318.05 | 327 / 328 | 92% | 3.47 | 164 / 178 |
| stomach | 100% | 1695.56 | 359 / 359 | 91% | 3.40 | 259 / 286 |
| liver | 100% | 2273.10 | 226 / 226 | 88% | 3.55 | 359 / 406 |
| intestine | 100% | 2317.07 | 964 / 966 | 89% | 3.18 | 467 / 527 |
| esophagus | 100% | 1351.35 | 1440 / 1445 | 88% | 3.73 | 161 / 183 |
| kidney | 100% | 2352.53 | 89 / 89 | 86% | 3.82 | 778 / 901 |
| breast | 100% | 2475.45 | 459 / 459 | 85% | 2.32 | 952 / 1118 |
| ovary | 100% | 2255.09 | 180 / 180 | 84% | 2.82 | 361 / 430 |
| adrenal gland | 100% | 2146.12 | 258 / 258 | 84% | 2.25 | 193 / 230 |
| lung | 100% | 3568.97 | 578 / 578 | 81% | 2.66 | 938 / 1155 |
| uterus | 100% | 2358.35 | 170 / 170 | 76% | 1.96 | 348 / 459 |
| skin | 97% | 1272.13 | 1751 / 1809 | 75% | 2.15 | 355 / 472 |
| bladder | 100% | 1493.19 | 21 / 21 | 72% | 1.88 | 362 / 504 |
| adipose | 100% | 2800.06 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4523.49 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1680.99 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 2071.12 | 906 / 929 | 0% | 0 | 0 / 0 |
| heart | 95% | 958.91 | 818 / 861 | 0% | 0 | 0 / 0 |
| muscle | 90% | 758.69 | 725 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 3.98 | 24 / 29 |
| eye | 0% | 0 | 0 / 0 | 66% | 1.54 | 53 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 60% | 1.40 | 27 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007288 | Biological process | sperm axoneme assembly |
| GO_0030317 | Biological process | flagellated sperm motility |
| GO_0036159 | Biological process | inner dynein arm assembly |
| GO_0003351 | Biological process | epithelial cilium movement involved in extracellular fluid movement |
| GO_0060285 | Biological process | cilium-dependent cell motility |
| GO_0036156 | Cellular component | inner dynein arm |
| GO_0005930 | Cellular component | axoneme |
| GO_0005858 | Cellular component | axonemal dynein complex |
| GO_0036126 | Cellular component | sperm flagellum |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005874 | Cellular component | microtubule |
| GO_0051959 | Molecular function | dynein light intermediate chain binding |
| GO_0008569 | Molecular function | minus-end-directed microtubule motor activity |
| GO_0045505 | Molecular function | dynein intermediate chain binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0003777 | Molecular function | microtubule motor activity |
| Gene name | DNAH1 |
| Protein name | Dynein axonemal heavy chain 1 (Axonemal beta dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7) Dynein axonemal heavy chain 1 |
| Synonyms | DHC7 DNAHC1 KIAA1410 |
| Description | FUNCTION: Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme . . |
| Accessions | H7C506 Q9P2D7 ENST00000480649.1 ENST00000490713.5 ENST00000420323.7 [Q9P2D7-4] H7C563 |
