Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| mast cell | 11 studies | 24% ± 8% | |
| ciliated cell | 9 studies | 41% ± 18% | |
| respiratory goblet cell | 6 studies | 36% ± 8% | |
| secretory cell | 6 studies | 34% ± 16% | |
| club cell | 5 studies | 35% ± 20% | |
| squamous epithelial cell | 4 studies | 46% ± 24% | |
| microglial cell | 4 studies | 23% ± 5% | |
| macrophage | 4 studies | 16% ± 1% | |
| epithelial cell | 3 studies | 34% ± 18% | |
| goblet cell | 3 studies | 43% ± 14% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 4 studies | 43% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 89% | 334.87 | 513 / 578 | 74% | 12.13 | 849 / 1155 |
| intestine | 57% | 1823.85 | 551 / 966 | 69% | 14.39 | 363 / 527 |
| brain | 32% | 68.24 | 850 / 2642 | 69% | 6.45 | 484 / 705 |
| esophagus | 43% | 478.48 | 620 / 1445 | 57% | 9.22 | 104 / 183 |
| spleen | 93% | 503.37 | 225 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 25.20 | 27 / 29 |
| stomach | 32% | 144.47 | 115 / 359 | 53% | 9.50 | 152 / 286 |
| breast | 63% | 331.69 | 288 / 459 | 22% | 2.43 | 244 / 1118 |
| pancreas | 3% | 3.70 | 9 / 328 | 81% | 49.61 | 145 / 178 |
| peripheral blood | 81% | 2168.50 | 755 / 929 | 0% | 0 | 0 / 0 |
| adipose | 75% | 472.19 | 905 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 29% | 38.19 | 6 / 21 | 44% | 10.06 | 223 / 504 |
| heart | 67% | 1512.48 | 578 / 861 | 0% | 0 | 0 / 0 |
| skin | 37% | 106.51 | 676 / 1809 | 22% | 1.08 | 102 / 472 |
| tonsil | 0% | 0 | 0 / 0 | 58% | 9.62 | 26 / 45 |
| uterus | 9% | 29.34 | 16 / 170 | 42% | 6.23 | 191 / 459 |
| thymus | 4% | 7.89 | 26 / 653 | 36% | 4.28 | 216 / 605 |
| kidney | 6% | 8.33 | 5 / 89 | 29% | 1.51 | 259 / 901 |
| prostate | 16% | 26.15 | 40 / 245 | 11% | 0.48 | 54 / 502 |
| liver | 9% | 26.62 | 21 / 226 | 14% | 0.92 | 55 / 406 |
| ovary | 3% | 6.27 | 6 / 180 | 15% | 0.90 | 65 / 430 |
| blood vessel | 10% | 26.53 | 134 / 1335 | 0% | 0 | 0 / 0 |
| adrenal gland | 3% | 3.80 | 8 / 258 | 2% | 0.09 | 5 / 230 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.06 | 2 / 80 |
| muscle | 2% | 3.19 | 20 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042448 | Biological process | progesterone metabolic process |
| GO_0042904 | Biological process | 9-cis-retinoic acid biosynthetic process |
| GO_0008202 | Biological process | steroid metabolic process |
| GO_0008209 | Biological process | androgen metabolic process |
| GO_0042572 | Biological process | retinol metabolic process |
| GO_0030855 | Biological process | epithelial cell differentiation |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0016854 | Molecular function | racemase and epimerase activity |
| GO_0004022 | Molecular function | alcohol dehydrogenase (NAD+) activity |
| GO_0004745 | Molecular function | all-trans-retinol dehydrogenase (NAD+) activity |
| GO_0047035 | Molecular function | testosterone dehydrogenase (NAD+) activity |
| GO_0047044 | Molecular function | androstan-3-alpha,17-beta-diol dehydrogenase activity |
| GO_0047023 | Molecular function | androsterone dehydrogenase activity |
| Gene name | DHRS9 |
| Protein name | Dehydrogenase/reductase SDR family member 9 (EC 1.1.1.209) (EC 1.1.1.53) (3-alpha hydroxysteroid dehydrogenase) (3-alpha-HSD) (NADP-dependent retinol dehydrogenase/reductase) (RDH-E2) (RDHL) (Retinol dehydrogenase 15) (EC 1.1.1.105) (Short chain dehydrogenase/reductase family 9C member 4) (Short-chain dehydrogenase/reductase retSDR8) (Tracheobronchial epithelial cell-specific retinol dehydrogenase) (RDH-TBE) Dehydrogenase/reductase 9 |
| Synonyms | SDR9C4 UNQ835/PRO1773 RDH15 |
| Description | FUNCTION: 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha-tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone . Also plays a role in the biosynthesis of retinoic acid from retinaldehyde . Can utilize both NADH and NADPH. . |
| Accessions | ENST00000428522.5 [Q9BPW9-1] ENST00000412271.1 [Q9BPW9-1] ENST00000436483.6 [Q9BPW9-1] Q9BPW9 C9J430 ENST00000432060.6 [Q9BPW9-4] ENST00000602501.5 [Q9BPW9-1] ENST00000421653.5 [Q9BPW9-2] ENST00000357546.6 [Q9BPW9-1] ENST00000674881.1 [Q9BPW9-1] ENST00000450153.1 |
