DET1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DET1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DET1 at tissue level.

III. Associated gene sets

GO_0032436Biological processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO_0016567Biological processprotein ubiquitination
GO_0065003Biological processprotein-containing complex assembly
GO_0080008Cellular componentCul4-RING E3 ubiquitin ligase complex
GO_0031461Cellular componentcullin-RING ubiquitin ligase complex
GO_0031464Cellular componentCul4A-RING E3 ubiquitin ligase complex
GO_0005634Cellular componentnucleus
GO_0044877Molecular functionprotein-containing complex binding
GO_1990756Molecular functionubiquitin-like ligase-substrate adaptor activity
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDET1
Protein nameDET1 homolog (De-etiolated-1 homolog)
DET1 partner of COP1 E3 ubiquitin ligase
Synonyms
DescriptionFUNCTION: Component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation. .

AccessionsQ7L5Y6
ENST00000558413.1
ENST00000557837.1
ENST00000557842.6
H0YK09
ENST00000268148.13 [Q7L5Y6-1]
ENST00000444300.1 [Q7L5Y6-2]
H0YN79
ENST00000564406.5 [Q7L5Y6-2]