Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 12 studies | 39% ± 11% | |
microglial cell | 10 studies | 26% ± 9% | |
endothelial cell | 8 studies | 26% ± 12% | |
kidney loop of Henle epithelial cell | 7 studies | 32% ± 15% | |
macrophage | 7 studies | 26% ± 6% | |
glutamatergic neuron | 4 studies | 34% ± 12% | |
dendritic cell | 3 studies | 17% ± 2% | |
epithelial cell | 3 studies | 42% ± 13% | |
GABAergic neuron | 3 studies | 41% ± 3% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 50% ± 3% | |
kidney distal convoluted tubule epithelial cell | 3 studies | 29% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 1940.04 | 180 / 180 | 97% | 69.26 | 417 / 430 |
thymus | 100% | 4368.42 | 653 / 653 | 96% | 63.93 | 579 / 605 |
stomach | 100% | 3365.79 | 359 / 359 | 94% | 38.42 | 270 / 286 |
kidney | 100% | 4131.58 | 89 / 89 | 93% | 31.49 | 837 / 901 |
breast | 98% | 1680.08 | 448 / 459 | 95% | 53.75 | 1065 / 1118 |
adrenal gland | 100% | 5691.40 | 258 / 258 | 93% | 39.32 | 213 / 230 |
prostate | 92% | 1033.48 | 226 / 245 | 99% | 34.60 | 499 / 502 |
intestine | 98% | 1984.31 | 945 / 966 | 93% | 33.05 | 490 / 527 |
liver | 83% | 586.06 | 187 / 226 | 93% | 27.75 | 377 / 406 |
uterus | 98% | 1802.29 | 167 / 170 | 53% | 30.03 | 241 / 459 |
esophagus | 93% | 1224.94 | 1339 / 1445 | 56% | 19.87 | 103 / 183 |
brain | 68% | 507.95 | 1795 / 2642 | 77% | 15.02 | 546 / 705 |
pancreas | 49% | 286.52 | 160 / 328 | 95% | 35.14 | 169 / 178 |
skin | 78% | 658.15 | 1406 / 1809 | 55% | 16.27 | 261 / 472 |
bladder | 67% | 571.71 | 14 / 21 | 65% | 19.90 | 327 / 504 |
lung | 41% | 288.93 | 236 / 578 | 73% | 25.39 | 844 / 1155 |
muscle | 100% | 8370.18 | 803 / 803 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 27.73 | 1 / 1 |
adipose | 96% | 1382.60 | 1161 / 1204 | 0% | 0 | 0 / 0 |
spleen | 88% | 957.30 | 213 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 65% | 606.38 | 866 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 49% | 9.07 | 22 / 45 |
heart | 43% | 254.85 | 367 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 28% | 4.39 | 8 / 29 |
eye | 0% | 0 | 0 / 0 | 14% | 1.96 | 11 / 80 |
peripheral blood | 0% | 2.33 | 3 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032007 | Biological process | negative regulation of TOR signaling |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0045792 | Biological process | negative regulation of cell size |
GO_0010508 | Biological process | positive regulation of autophagy |
GO_1903940 | Biological process | negative regulation of TORC2 signaling |
GO_2001236 | Biological process | regulation of extrinsic apoptotic signaling pathway |
GO_1904262 | Biological process | negative regulation of TORC1 signaling |
GO_0005765 | Cellular component | lysosomal membrane |
GO_0004860 | Molecular function | protein kinase inhibitor activity |
GO_0070300 | Molecular function | phosphatidic acid binding |
GO_0030291 | Molecular function | protein serine/threonine kinase inhibitor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DEPTOR |
Protein name | DEP domain-containing mTOR-interacting protein (hDEPTOR) (DEP domain-containing protein 6) |
Synonyms | DEPDC6 |
Description | FUNCTION: Negative regulator of the mTORC1 and mTORC2 complexes: inhibits the protein kinase activity of MTOR, thereby inactivating both complexes . DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy . In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity . . |
Accessions | ENST00000523492.5 [Q8TB45-2] ENST00000286234.6 [Q8TB45-1] Q8TB45 |