Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 16 studies | 35% ± 14% | |
| glutamatergic neuron | 5 studies | 34% ± 18% | |
| classical monocyte | 3 studies | 22% ± 2% | |
| non-classical monocyte | 3 studies | 23% ± 4% | |
| plasmablast | 3 studies | 25% ± 2% | |
| GABAergic neuron | 3 studies | 31% ± 13% | |
| neuron | 3 studies | 21% ± 2% |
Insufficient scRNA-seq data for expression of DENND6B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 1639.90 | 653 / 653 | 100% | 11.63 | 603 / 605 |
| brain | 99% | 3082.45 | 2627 / 2642 | 100% | 14.96 | 705 / 705 |
| prostate | 100% | 1427.15 | 244 / 245 | 99% | 7.69 | 499 / 502 |
| ovary | 99% | 919.21 | 179 / 180 | 98% | 7.13 | 423 / 430 |
| uterus | 100% | 1509.35 | 170 / 170 | 94% | 6.46 | 432 / 459 |
| adrenal gland | 100% | 842.34 | 257 / 258 | 93% | 6.96 | 215 / 230 |
| breast | 96% | 844.27 | 441 / 459 | 96% | 6.93 | 1075 / 1118 |
| kidney | 100% | 1536.93 | 89 / 89 | 92% | 9.00 | 827 / 901 |
| lung | 98% | 1149.52 | 565 / 578 | 92% | 5.61 | 1066 / 1155 |
| pancreas | 93% | 596.06 | 304 / 328 | 97% | 8.25 | 173 / 178 |
| bladder | 90% | 595.10 | 19 / 21 | 88% | 4.55 | 446 / 504 |
| esophagus | 90% | 568.09 | 1304 / 1445 | 86% | 3.87 | 158 / 183 |
| intestine | 99% | 855.85 | 954 / 966 | 75% | 3.43 | 395 / 527 |
| stomach | 91% | 539.54 | 327 / 359 | 80% | 3.68 | 228 / 286 |
| skin | 73% | 370.03 | 1323 / 1809 | 92% | 5.03 | 434 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 25.80 | 29 / 29 |
| spleen | 100% | 1263.77 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.25 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 99% | 4.47 | 79 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 4.47 | 42 / 45 |
| adipose | 87% | 517.13 | 1052 / 1204 | 0% | 0 | 0 / 0 |
| liver | 17% | 67.54 | 39 / 226 | 40% | 2.26 | 164 / 406 |
| peripheral blood | 55% | 673.21 | 510 / 929 | 0% | 0 | 0 / 0 |
| blood vessel | 47% | 225.17 | 630 / 1335 | 0% | 0 | 0 / 0 |
| heart | 27% | 114.54 | 235 / 861 | 0% | 0 | 0 / 0 |
| muscle | 3% | 9.81 | 21 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005829 | Cellular component | cytosol |
| GO_0055037 | Cellular component | recycling endosome |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| Gene name | DENND6B |
| Protein name | DENN domain containing 6B Protein DENND6B (DENN domain-containing protein 6B) |
| Synonyms | FAM116B |
| Description | FUNCTION: Guanine nucleotide exchange factor (GEF) for RAB14. Also has some, lesser GEF activity towards RAB35. . |
| Accessions | Q8NEG7 ENST00000433760.1 ENST00000413817.8 H0Y7N0 |
