DEFB103A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DEFB103A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DEFB103A at tissue level.

III. Associated gene sets

GO_0050829Biological processdefense response to Gram-negative bacterium
GO_0031640Biological processkilling of cells of another organism
GO_0050830Biological processdefense response to Gram-positive bacterium
GO_0051873Biological processkilling by host of symbiont cells
GO_0060326Biological processcell chemotaxis
GO_0042742Biological processdefense response to bacterium
GO_0050918Biological processpositive chemotaxis
GO_0005615Cellular componentextracellular space
GO_0005796Cellular componentGolgi lumen
GO_0005576Cellular componentextracellular region
GO_0042056Molecular functionchemoattractant activity
GO_0005515Molecular functionprotein binding
GO_0031731Molecular functionCCR6 chemokine receptor binding

IV. Literature review

[source]
Gene nameDEFB103A
Protein nameBeta-defensin 3
Beta-defensin 103 (Beta-defensin 3) (BD-3) (DEFB-3) (HBD3) (hBD-3) (Defensin, beta 103) (Defensin-like protein)
SynonymsDEFB3;
DEFB103B
DEFB103
BD3
DescriptionFUNCTION: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. .

AccessionsENST00000318124.3
ENST00000314357.4
Q5U7J2
ENST00000613448.2
ENST00000646344.2
P81534
ENST00000642635.2