DECR2 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	4 studies	26% ± 9%	Explore
hepatocyte	3 studies	31% ± 12%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DECR2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	7348.54	226 / 226	100%	52.11	405 / 406
prostate	100%	1171.75	245 / 245	99%	19.60	499 / 502
brain	100%	678.33	2629 / 2642	100%	11.35	703 / 705
pancreas	100%	1015.25	328 / 328	98%	15.00	175 / 178
intestine	100%	1342.70	966 / 966	98%	20.93	518 / 527
breast	100%	920.91	459 / 459	98%	17.57	1091 / 1118
skin	100%	817.40	1808 / 1809	97%	12.56	459 / 472
stomach	100%	859.97	359 / 359	97%	17.52	277 / 286
uterus	100%	777.42	170 / 170	97%	13.16	444 / 459
kidney	100%	2327.58	89 / 89	96%	30.83	864 / 901
lung	99%	609.00	574 / 578	96%	11.80	1109 / 1155
bladder	100%	842.00	21 / 21	95%	14.99	480 / 504
adrenal gland	100%	2472.79	258 / 258	91%	14.39	210 / 230
esophagus	100%	869.60	1444 / 1445	90%	9.02	165 / 183
ovary	100%	696.86	180 / 180	89%	8.18	381 / 430
thymus	100%	590.01	652 / 653	86%	7.38	521 / 605
adipose	100%	963.66	1204 / 1204	0%	0	0 / 0
muscle	100%	1058.14	803 / 803	0%	0	0 / 0
spleen	100%	636.29	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	22.98	1 / 1
blood vessel	100%	616.17	1329 / 1335	0%	0	0 / 0
heart	98%	538.66	848 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	98%	12.22	78 / 80
tonsil	0%	0	0 / 0	91%	6.89	41 / 45
lymph node	0%	0	0 / 0	86%	15.57	25 / 29
peripheral blood	56%	176.33	520 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006631	Biological process	fatty acid metabolic process
GO_0006636	Biological process	unsaturated fatty acid biosynthetic process
GO_0033540	Biological process	fatty acid beta-oxidation using acyl-CoA oxidase
GO_0005778	Cellular component	peroxisomal membrane
GO_0005829	Cellular component	cytosol
GO_0005777	Cellular component	peroxisome
GO_0008670	Molecular function	2,4-dienoyl-CoA reductase (NADPH) activity
GO_0005515	Molecular function	protein binding
GO_0019166	Molecular function	trans-2-enoyl-CoA reductase (NADPH) activity

Gene name	DECR2
Protein name	Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (pDCR) (EC 1.3.1.124) (2,4-dienoyl-CoA reductase 2) (Short chain dehydrogenase/reductase family 17C member 1) Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (EC 1.3.1.124) (2,4-dienoyl-CoA reductase 2)
Synonyms	SDR17C1 PDCR hCG_2039398
Description	FUNCTION: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. .
Accessions	Q9NUI1 ENST00000633348.1 ENST00000633596.1 ENST00000633624.1 ENST00000633923.1 A0A0J9YY83 ENST00000429116.1 H7C078 ENST00000627716.2 A0A0J9YXZ6 ENST00000631856.1 [Q9NUI1-2] ENST00000632810.1 ENST00000437024.5 ENST00000633559.1 ENST00000630165.1 ENST00000631605.1 ENST00000613476.3 [Q9NUI1-1] ENST00000632042.1 A0A0J9YWI0 ENST00000631983.1 ENST00000445291.5 ENST00000633143.1 ENST00000424398.6 Q4VXZ8 ENST00000439661.5 [Q9NUI1-2] ENST00000633148.1 ENST00000633025.1 G3V0I9 ENST00000219481.10 [Q9NUI1-1]

DECR2 report