Insufficient scRNA-seq data for expression of DDO at single-cell level.
Insufficient scRNA-seq data for expression of DDO at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 502.76 | 226 / 226 | 98% | 13.56 | 397 / 406 |
brain | 99% | 376.34 | 2615 / 2642 | 99% | 13.30 | 695 / 705 |
kidney | 100% | 416.33 | 89 / 89 | 95% | 16.45 | 853 / 901 |
thymus | 97% | 145.66 | 635 / 653 | 89% | 7.43 | 539 / 605 |
adrenal gland | 100% | 789.37 | 258 / 258 | 80% | 11.50 | 183 / 230 |
breast | 99% | 175.41 | 454 / 459 | 76% | 6.15 | 850 / 1118 |
pancreas | 90% | 110.16 | 296 / 328 | 84% | 5.28 | 150 / 178 |
prostate | 98% | 150.81 | 239 / 245 | 60% | 2.37 | 299 / 502 |
intestine | 98% | 190.12 | 951 / 966 | 54% | 3.67 | 283 / 527 |
lung | 99% | 235.15 | 573 / 578 | 50% | 2.78 | 578 / 1155 |
uterus | 98% | 188.28 | 167 / 170 | 44% | 3.32 | 201 / 459 |
bladder | 86% | 147.81 | 18 / 21 | 50% | 3.37 | 251 / 504 |
stomach | 55% | 96.53 | 198 / 359 | 49% | 3.58 | 141 / 286 |
spleen | 100% | 192.11 | 240 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 241.44 | 1329 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 181.07 | 1194 / 1204 | 0% | 0 | 0 / 0 |
muscle | 99% | 346.35 | 796 / 803 | 0% | 0 | 0 / 0 |
heart | 97% | 817.69 | 833 / 861 | 0% | 0 | 0 / 0 |
esophagus | 57% | 64.84 | 825 / 1445 | 24% | 1.23 | 44 / 183 |
ovary | 23% | 21.90 | 41 / 180 | 50% | 2.04 | 213 / 430 |
skin | 29% | 25.12 | 521 / 1809 | 40% | 3.10 | 190 / 472 |
lymph node | 0% | 0 | 0 / 0 | 38% | 1.15 | 11 / 29 |
tonsil | 0% | 0 | 0 / 0 | 33% | 1.21 | 15 / 45 |
peripheral blood | 10% | 7.49 | 91 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 0.14 | 3 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0010646 | Biological process | regulation of cell communication |
GO_0007320 | Biological process | insemination |
GO_0007625 | Biological process | grooming behavior |
GO_0050877 | Biological process | nervous system process |
GO_0042445 | Biological process | hormone metabolic process |
GO_0006533 | Biological process | aspartate catabolic process |
GO_0019478 | Biological process | D-amino acid catabolic process |
GO_0005829 | Cellular component | cytosol |
GO_0005777 | Cellular component | peroxisome |
GO_0005782 | Cellular component | peroxisomal matrix |
GO_0005737 | Cellular component | cytoplasm |
GO_0008445 | Molecular function | D-aspartate oxidase activity |
GO_0071949 | Molecular function | FAD binding |
GO_0047821 | Molecular function | D-glutamate oxidase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DDO |
Protein name | D-aspartate oxidase D-aspartate oxidase (DASOX) (DASPO) (DDO) (EC 1.4.3.1) |
Synonyms | |
Description | FUNCTION: Selectively catalyzes the oxidative deamination of acidic amino acids . Suppresses the level of D-aspartate in the brain, an amino acid that can act as an agonist for glutamate receptors . Protects the organism from the toxicity of D-amino acids (By similarity). May also function in the intestine (By similarity). . |
Accessions | ENST00000479373.1 Q99489 F2Z2E0 ENST00000368923.8 [Q99489-2] ENST00000368924.9 [Q99489-1] |