DCT | OmnibusX

Name	Number of supported studies	Average coverage
melanocyte	7 studies	65% ± 30%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of DCT at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	73%	3118.17	1318 / 1809	91%	575.59	431 / 472
brain	92%	170.18	2440 / 2642	71%	2.81	502 / 705
adrenal gland	88%	109.13	228 / 258	6%	0.09	14 / 230
ovary	91%	105.26	163 / 180	2%	0.03	8 / 430
prostate	77%	91.06	188 / 245	2%	0.03	9 / 502
eye	0%	0	0 / 0	71%	12.73	57 / 80
uterus	69%	77.55	117 / 170	2%	0.06	10 / 459
blood vessel	71%	71.82	947 / 1335	0%	0	0 / 0
thymus	66%	60.02	433 / 653	2%	0.03	14 / 605
pancreas	66%	54.51	216 / 328	0%	0	0 / 178
intestine	55%	60.95	536 / 966	3%	0.16	17 / 527
bladder	57%	53.86	12 / 21	1%	0.02	6 / 504
breast	53%	91.75	241 / 459	3%	0.14	30 / 1118
esophagus	52%	57.30	757 / 1445	1%	0.05	2 / 183
adipose	50%	45.36	600 / 1204	0%	0	0 / 0
muscle	45%	33.17	364 / 803	0%	0	0 / 0
kidney	27%	18.43	24 / 89	10%	0.24	89 / 901
lung	31%	22.07	182 / 578	1%	0.02	13 / 1155
stomach	24%	25.81	85 / 359	5%	0.15	13 / 286
liver	24%	17.58	54 / 226	1%	0.04	6 / 406
heart	20%	13.59	170 / 861	0%	0	0 / 0
spleen	20%	10.83	47 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.05	1 / 29
tonsil	0%	0	0 / 0	2%	0.03	1 / 45
peripheral blood	1%	0.25	5 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0002052	Biological process	positive regulation of neuroblast proliferation
GO_0021847	Biological process	ventricular zone neuroblast division
GO_0048066	Biological process	developmental pigmentation
GO_0009637	Biological process	response to blue light
GO_0008544	Biological process	epidermis development
GO_0006583	Biological process	melanin biosynthetic process from tyrosine
GO_0048468	Biological process	cell development
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0042470	Cellular component	melanosome
GO_0033162	Cellular component	melanosome membrane
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0004167	Molecular function	dopachrome isomerase activity
GO_0016491	Molecular function	oxidoreductase activity
GO_0005507	Molecular function	copper ion binding
GO_0005515	Molecular function	protein binding

Gene name	DCT
Protein name	DCT L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) L-dopachrome tautomerase (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2)
Synonyms	TYRP2
Description	FUNCTION: Plays a role in melanin biosynthesis . Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). .
Accessions	ENST00000377028.10 [P40126-1] ENST00000483392.6 ENST00000446125.1 [P40126-2] P40126 Q0PK43 A0A0A0MTD3

DCT report