Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 4 studies | 37% ± 9% | |
| astrocyte | 4 studies | 30% ± 9% | |
| oligodendrocyte | 3 studies | 20% ± 2% | |
| oligodendrocyte precursor cell | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 1324.33 | 180 / 180 | 100% | 22.43 | 430 / 430 |
| prostate | 100% | 1614.91 | 245 / 245 | 100% | 14.86 | 502 / 502 |
| thymus | 100% | 1074.44 | 653 / 653 | 100% | 16.54 | 605 / 605 |
| intestine | 100% | 1906.89 | 966 / 966 | 100% | 12.71 | 526 / 527 |
| skin | 100% | 944.44 | 1807 / 1809 | 100% | 13.97 | 471 / 472 |
| breast | 100% | 1001.76 | 459 / 459 | 99% | 16.77 | 1112 / 1118 |
| stomach | 99% | 1041.20 | 356 / 359 | 100% | 13.21 | 286 / 286 |
| adrenal gland | 100% | 1669.82 | 258 / 258 | 99% | 16.16 | 228 / 230 |
| kidney | 100% | 763.46 | 89 / 89 | 99% | 12.00 | 892 / 901 |
| pancreas | 97% | 519.65 | 319 / 328 | 100% | 11.57 | 178 / 178 |
| brain | 96% | 470.88 | 2548 / 2642 | 100% | 10.46 | 705 / 705 |
| uterus | 100% | 2512.29 | 170 / 170 | 95% | 10.98 | 434 / 459 |
| bladder | 100% | 1940.76 | 21 / 21 | 94% | 10.40 | 474 / 504 |
| esophagus | 100% | 1252.95 | 1443 / 1445 | 94% | 10.06 | 172 / 183 |
| lung | 100% | 875.17 | 576 / 578 | 93% | 9.44 | 1075 / 1155 |
| liver | 97% | 528.87 | 219 / 226 | 92% | 6.47 | 372 / 406 |
| blood vessel | 100% | 1367.17 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 16.02 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 13.94 | 29 / 29 |
| spleen | 100% | 947.06 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.97 | 1 / 1 |
| adipose | 100% | 911.75 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 98% | 619.35 | 790 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 9.32 | 42 / 45 |
| heart | 72% | 251.49 | 620 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 69% | 416.33 | 642 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0031087 | Biological process | deadenylation-independent decapping of nuclear-transcribed mRNA |
| GO_0000184 | Biological process | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| GO_0000290 | Biological process | deadenylation-dependent decapping of nuclear-transcribed mRNA |
| GO_0000932 | Cellular component | P-body |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0008047 | Molecular function | enzyme activator activity |
| GO_0140933 | Molecular function | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0003729 | Molecular function | mRNA binding |
| Gene name | DCP1B |
| Protein name | 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase (EC 3.6.1.62) Decapping mRNA 1B mRNA-decapping enzyme 1B (EC 3.6.1.62) |
| Synonyms | |
| Description | FUNCTION: May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity). . |
| Accessions | ENST00000535873.2 F5H4R4 ENST00000280665.11 [Q8IZD4-1] ENST00000540622.1 ENST00000647122.2 [Q8IZD4-1] F5GZK9 ENST00000543381.5 B4DVJ6 Q8IZD4 |