CYSLTR2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CYSLTR2 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0061737Biological processleukotriene signaling pathway
GO_0007218Biological processneuropeptide signaling pathway
GO_0005575Cellular componentcellular_component
GO_0005886Cellular componentplasma membrane
GO_0004974Molecular functionleukotriene receptor activity
GO_0008528Molecular functionG protein-coupled peptide receptor activity
GO_0001631Molecular functioncysteinyl leukotriene receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCYSLTR2
Protein nameCysteinyl leukotriene receptor 2 (G-protein coupled receptor protein)
Cysteinyl leukotriene receptor 2 (CysLTR2) (G-protein coupled receptor GPCR21) (hGPCR21) (G-protein coupled receptor HG57) (HPN321)
Cysteinyl leukotriene receptor 2
Cysteinyl leukotriene receptor 2 splice variant I (Cysteinyl leukotriene receptor 2 splice variant III) (Cysteinyl leukotriene receptor 2 splice variant IV) (Cysteinyl leukotriene receptor 2 splice variant V) (Cysteinyl leukotriene receptor 2 splice variant VII)
SynonymsCYSLT2R
CYSLT2
KPG_011
PSEC0146
hCG_1647464
DescriptionFUNCTION: Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.

AccessionsENST00000682523.1
ENST00000621321.1
A4ZKH2
Q5KU17
A0A1B0GXM0
Q9NS75
ENST00000282018.4
ENST00000622559.4
ENST00000614739.4
ENST00000617562.4